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ZNF19 Antibody (B-11): sc-166026

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Datasheets
  • ZNF19 Antibody (B-11) is a mouse monoclonal IgG1 κ ZNF19 antibody provided at 200 µg/ml
  • raised against amino acids 71-164 mapping near the N-terminus of ZNF19 of human origin
  • ZNF19 Antibody (B-11) is recommended for detection of ZNF19 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-ZNF19 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • TransCruz reagent for ChIP application (sc-166026 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF19 Antibody (B-11) for WB applications. These reagents are now offered in bundles with ZNF19 Antibody (B-11) (see ordering information below).
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    ZNF19 Antibody (B-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF19 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF19 (B-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF19, also known as KOX12, is a member of the Krüppel C2H2-type zinc-finger family of transcriptional regulators, characterized by its 458 amino acid length, which includes 10 C2H2-type zinc fingers and a single KRAB domain. The KRAB domain is particularly significant as it is believed to interact with the KAP1 protein, facilitating the recruitment of histone-modifying enzymes that play a crucial role in chromatin remodeling and gene expression regulation. The expression of ZNF19 is predominantly localized in the nucleus, underscoring its essential function in transcriptional regulation and cellular processes. Anti-ZNF19 antibody (B-11) enables researchers to gain valuable insights into the mechanisms of gene regulation and the role of zinc-finger proteins in various biological contexts.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    ZNF19 Antibody (B-11) References:

    1. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL.  |  Rousseau-Merck, MF., et al. 2002. Cytogenet Genome Res. 98: 147-53. PMID: 12697996
    2. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor.  |  Sun, Y., et al. 2003. IUBMB Life. 55: 127-31. PMID: 12822888
    3. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
    4. A novel subfamily of zinc finger genes involved in embryonic development.  |  Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
    5. A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE.  |  Li, Y., et al. 2006. Mol Biol Rep. 33: 287-94. PMID: 17089209
    6. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
    7. Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity.  |  Zhong, Z., et al. 2007. J Biochem Mol Biol. 40: 517-24. PMID: 17669267
    8. Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.  |  Rousseau-Merck, MF., et al. 1993. Hum Genet. 92: 583-7. PMID: 8262519
    9. Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24.  |  Cannizzaro, LA., et al. 1993. Hum Genet. 91: 383-5. PMID: 8500793

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    ZNF19 Antibody (B-11)

    sc-166026
    200 µg/ml
    $322.00

    ZNF19 Antibody (B-11): m-IgG Fc BP-HRP Bundle

    sc-528895
    200 µg Ab; 10 µg BP
    $361.00

    ZNF19 Antibody (B-11): m-IgGκ BP-HRP Bundle

    sc-521487
    200 µg Ab, 40 µg BP
    $361.00

    ZNF19 Antibody (B-11): m-IgG1 BP-HRP Bundle

    sc-543198
    200 µg Ab; 20 µg BP
    $361.00

    ZNF19 Antibody (B-11) X

    sc-166026 X
    200 µg/0.1 ml
    $322.00

    ZNF19 Antibody (B-11) AC

    sc-166026 AC
    500 µg/ml, 25% agarose
    $424.00

    ZNF19 Antibody (B-11) HRP

    sc-166026 HRP
    200 µg/ml
    $322.00

    ZNF19 Antibody (B-11) FITC

    sc-166026 FITC
    200 µg/ml
    $336.00

    ZNF19 Antibody (B-11) PE

    sc-166026 PE
    200 µg/ml
    $349.00

    ZNF19 Antibody (B-11) Alexa Fluor® 488

    sc-166026 AF488
    200 µg/ml
    $364.00

    ZNF19 Antibody (B-11) Alexa Fluor® 546

    sc-166026 AF546
    200 µg/ml
    $364.00

    ZNF19 Antibody (B-11) Alexa Fluor® 594

    sc-166026 AF594
    200 µg/ml
    $364.00

    ZNF19 Antibody (B-11) Alexa Fluor® 647

    sc-166026 AF647
    200 µg/ml
    $364.00

    ZNF19 Antibody (B-11) Alexa Fluor® 680

    sc-166026 AF680
    200 µg/ml
    $364.00

    ZNF19 Antibody (B-11) Alexa Fluor® 790

    sc-166026 AF790
    200 µg/ml
    $364.00

    When should the TransCruz reagent sc-166026 X be used instead of the standard form sc-166026?

    Asked by: Dr Ninau Qelp
    Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
    Answered by: Technical Support
    Date published: 2017-02-28
    • y_2026, m_5, d_9, h_13CST
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    Rated 5 out of 5 by from Produced nice Western blot data of ZNF19Produced nice Western blot data of ZNF19 expression in HeLa nuclear extract and Jurkat whole cell lysate . -SCBT QC
    Date published: 2014-02-19
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    ZNF19 Antibody (B-11) is rated 5.0 out of 5 by 1.
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