ZNF167 Antibody (G-4): sc-376321
- ZNF167 Antibody (G-4) is a mouse monoclonal IgG1 κ ZNF167 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 5-25 at the N-terminus of ZNF167 of human origin
- ZNF167 Antibody (G-4) is recommended for detection of ZNF167 of human origin by WB, IP, IF and ELISA
- Anti-ZNF167 Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-376321 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZNF167 Antibody (G-4) for WB applications. These reagents are now offered in bundles with ZNF167 Antibody (G-4) (see ordering information below).
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SEE ALSO...
ZNF167 Antibody (G-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF167 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF167 (G-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF167, also known as zinc finger protein with KRAB and SCAN domains 7, is a member of the Krüppel C2H2-type zinc-finger protein family and consists of 754 amino acids featuring thirteen C2H2-type zinc fingers, one KRAB domain, and one SCAN box domain. ZNF167 is primarily localized in the nucleus, where ZNF167 plays a crucial role in transcriptional regulation, influencing gene expression and cellular function. The presence of the KRAB domain is particularly significant as this domain interacts with KAP1, recruiting histone-modifying proteins that can alter chromatin structure and thereby modulate transcriptional activity. Additionally, ZNF167 exists in two isoforms due to alternative splicing, which may contribute to functional diversity in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF167 Antibody (G-4) References:
- Identification and characterization of human ZNF274 cDNA, which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability. | Yano, K., et al. 2000. Genomics. 65: 75-80. PMID: 10777669
- The identification and characterization of KRAB-domain-containing zinc finger proteins. | Constantinou-Deltas, CD., et al. 1992. Genomics. 12: 581-9. PMID: 1559709
- The SCAN domain family of zinc finger transcription factors. | Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
- The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression. | Sripathy, SP., et al. 2006. Mol Cell Biol. 26: 8623-38. PMID: 16954381
- The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. | Bellefroid, EJ., et al. 1991. Proc Natl Acad Sci U S A. 88: 3608-12. PMID: 2023909
- Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. | Vissing, H., et al. 1995. FEBS Lett. 369: 153-7. PMID: 7649249
- Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins. | Pengue, G., et al. 1994. Nucleic Acids Res. 22: 2908-14. PMID: 8065901
- The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. | Witzgall, R., et al. 1994. Proc Natl Acad Sci U S A. 91: 4514-8. PMID: 8183940
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF167 Antibody (G-4) | sc-376321 | 200 µg/ml | $316.00 | |||
ZNF167 Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-527523 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF167 Antibody (G-4): m-IgG1 BP-HRP Bundle | sc-532896 | 200 µg Ab; 20 µg BP | $354.00 | |||
ZNF167 Antibody (G-4) X | sc-376321 X | 200 µg/0.1 ml | $316.00 | |||
ZNF167 Antibody (G-4) AC | sc-376321 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF167 Antibody (G-4) HRP | sc-376321 HRP | 200 µg/ml | $316.00 | |||
ZNF167 Antibody (G-4) FITC | sc-376321 FITC | 200 µg/ml | $330.00 | |||
ZNF167 Antibody (G-4) PE | sc-376321 PE | 200 µg/ml | $343.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 488 | sc-376321 AF488 | 200 µg/ml | $357.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 546 | sc-376321 AF546 | 200 µg/ml | $357.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 594 | sc-376321 AF594 | 200 µg/ml | $357.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 647 | sc-376321 AF647 | 200 µg/ml | $357.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 680 | sc-376321 AF680 | 200 µg/ml | $357.00 | |||
ZNF167 Antibody (G-4) Alexa Fluor® 790 | sc-376321 AF790 | 200 µg/ml | $357.00 | |||
ZNF167 (G-4) Neutralizing Peptide | sc-376321 P | 100 µg/0.5 ml | $68.00 |