ZFAND2B Antibody (A-1): sc-398078
- ZFAND2B Antibody (A-1) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 129-152 within an internal region of ZFAND2B of human origin
- recommended for detection of ZFAND2B isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG3 BP-HRP is the preferred secondary detection reagent for ZFAND2B Antibody (A-1) for WB applications. This reagent is now offered in a bundle with ZFAND2B Antibody (A-1) (see ordering information below).
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ZFAND2B Antibody (A-1) is a mouse monoclonal IgG3 antibody that detects ZFAND2B in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZFAND2B, also known as AN1-type zinc finger protein 2B, is a 257 amino acid protein characterized by the presence of two AN1-type zinc fingers and two ubiquitin-interacting motif repeats, which play a crucial role in the ubiquitination pathway. The AN1-type zinc finger domain is conserved across various species, indicating fundamental importance in cellular processes. ZFAND2B is primarily located in the nucleus, where ZFAND2B is involved in transcriptional regulation, thereby influencing gene expression and cellular responses to stress. ZFAND2B′s ability to interact with ubiquitin-like domains suggests involvement in the modulation of protein stability and degradation, which is vital for maintaining cellular homeostasis and regulating various signaling pathways. Additionally, ZFAND2B exists in two isoforms due to alternative splicing, which may provide functional diversity and adaptability in response to different cellular contexts. With multifaceted roles in transcriptional regulation and protein interactions, ZFAND2B is an essential component in understanding the complexities of gene expression and cellular function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZFAND2B Antibody (A-1) | sc-398078 | 200 µg/ml | $322.00 | |||
ZFAND2B Antibody (A-1): m-IgG3 BP-HRP Bundle | sc-550504 | 200 µg Ab; 40 µg BP | $361.00 | |||
ZFAND2B (A-1) Neutralizing Peptide | sc-398078 P | 100 µg/0.5 ml | $69.00 |