ZC3H7A Antibody (B-3): sc-398981
- ZC3H7A Antibody (B-3) is a mouse monoclonal IgG1 κ ZC3H7A antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 885-948 mapping near the C-terminus of ZC3H7A of human origin
- ZC3H7A Antibody (B-3) is recommended for detection of ZC3H7A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZC3H7A Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for ZC3H7A Antibody (B-3) for WB applications. This reagent is now offered in a bundle with ZC3H7A Antibody (B-3) (see ordering information below).
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ZC3H7A Antibody (B-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZC3H7A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-ZC3H7A antibody (B-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZC3H7A, also known as ZC3H7, HSPC055, or ZC3HDC7, is a 971 amino acid protein characterized by a C3H1-type zinc finger domain, three C3H1-type zinc fingers, and three tetratricopeptide repeats, which are crucial for protein-protein interactions. ZC3H7A belongs to the ZC3H12 family and is primarily localized in the nucleus, where ZC3H7A plays a significant role in regulating gene expression and cellular responses to stress. The zinc finger domain facilitates ZC3H7A binding to RNA and DNA, influencing various cellular processes, including apoptosis and immune responses. ZC3H7A is encoded by a gene located on human chromosome 16p13.13, a region associated with several genetic disorders, including giant axonal neuropathy and Crohn′s disease, highlighting ZC3H7A′s potential relevance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZC3H7A Antibody (B-3) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- Giant axonal neuropathy (GAN): case report and two novel mutations in the gigaxonin gene. | Kuhlenbäumer, G., et al. 2002. Neurology. 58: 1273-6. PMID: 11971098
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Advances in the genetics of inflammatory bowel disease. | Cho, JH. 2004. Curr Gastroenterol Rep. 6: 467-73. PMID: 15527676
- [Progress in the study of KRAB zinc finger protein]. | Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZC3H7A Antibody (B-3) | sc-398981 | 200 µg/ml | $322.00 | |||
ZC3H7A Antibody (B-3): m-IgG1 BP-HRP Bundle | sc-531770 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZC3H7A Antibody (B-3) AC | sc-398981 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZC3H7A Antibody (B-3) HRP | sc-398981 HRP | 200 µg/ml | $322.00 | |||
ZC3H7A Antibody (B-3) FITC | sc-398981 FITC | 200 µg/ml | $336.00 | |||
ZC3H7A Antibody (B-3) PE | sc-398981 PE | 200 µg/ml | $349.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 488 | sc-398981 AF488 | 200 µg/ml | $364.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 546 | sc-398981 AF546 | 200 µg/ml | $364.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 594 | sc-398981 AF594 | 200 µg/ml | $364.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 647 | sc-398981 AF647 | 200 µg/ml | $364.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 680 | sc-398981 AF680 | 200 µg/ml | $364.00 | |||
ZC3H7A Antibody (B-3) Alexa Fluor® 790 | sc-398981 AF790 | 200 µg/ml | $364.00 |