Molecular structure of WS 3, CAS Number: 39711-79-0
WS 3 (CAS 39711-79-0)
Alternate Names:
N-Ethyl-p-methane-3-carboxamide, Ethyl menthane carboxamide, Framidice 3, Menthol Carboxamide WS-3
Application:
WS 3 is an agent that acts as aTRPM8 receptor agonist
CAS Number:
39711-79-0
Purity:
≥98%
Molecular Weight:
211.34
Molecular Formula:
C13H25NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
TRPM8 receptors agonist (EC50 = 3.7 μM) and cooling agent.
WS 3 (CAS 39711-79-0) References
- Pseudomonas syringae effector AvrPtoB suppresses basal defence in Arabidopsis. | de Torres, M., et al. 2006. Plant J. 47: 368-82. PMID: 16792692
- Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. | Beck, B., et al. 2007. Cell Calcium. 41: 285-94. PMID: 16949669
- Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship. | Sherkheli, MA., et al. 2010. J Pharm Pharm Sci. 13: 242-53. PMID: 20816009
- Novel menthol-derived cooling compounds activate primary and second-order trigeminal sensory neurons and modulate lingual thermosensitivity. | Klein, AH., et al. 2011. Chem Senses. 36: 649-58. PMID: 21511802
- Differences in flavourant levels and synthetic coolant use between USA, EU and Canadian Juul products. | Erythropel, HC., et al. 2020. Tob Control. 30: 453-5. PMID: 32341193
- Flavour chemicals, synthetic coolants and pulegone in popular mint-flavoured and menthol-flavoured e-cigarettes. | Omaiye, EE., et al. 2022. Tob Control. 31: e3-e9. PMID: 34193607
- Suppressive Effects of Transient Receptor Potential Melastatin 8 Agonist on Epileptiform Discharges and Epileptic Seizures. | Moriyama, H., et al. 2021. Front Pharmacol. 12: 766782. PMID: 34658898
- Synthetic Cooling Agents in US-marketed E-cigarette Refill Liquids and Popular Disposable E-cigarettes: Chemical Analysis and Risk Assessment. | Jabba, SV., et al. 2022. Nicotine Tob Res. 24: 1037-1046. PMID: 35167696
- Ice flavours and non-menthol synthetic cooling agents in e-cigarette products: a review. | Leventhal, AM., et al. 2022. Tob Control.. PMID: 35483721
- Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant. | Omaiye, EE., et al. 2022. Chem Res Toxicol. 35: 1344-1358. PMID: 35849830
- Sulfur-doped graphene/transition metal dichalcogenide heterostructured hybrids with electrocatalytic activity toward the hydrogen evolution reaction. | Kagkoura, A., et al. 2019. Nanoscale Adv. 1: 1489-1496. PMID: 36132594
Inhibitor of:
IKKα.Activator of:
TRPM8.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WS 3, 25 g | sc-204401 | 25 g | $61.00 | |||
WS 3, 100 g | sc-204401A | 100 g | $144.00 |