WDR93 Antibody (A-5): sc-393763
- WDR93 Antibody (A-5) is a mouse monoclonal IgG2a κ WDR93 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 43-70 near the N-terminus of WDR93 of human origin
- WDR93 Antibody (A-5) is recommended for detection of WDR93 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- Anti-WDR93 Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for WDR93 Antibody (A-5) for WB applications. These reagents are now offered in bundles with WDR93 Antibody (A-5) (see ordering information below).
WDR93 Antibody (A-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects WDR93 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). WDR93 Antibody (A-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. WDR93 consists of 686 amino acids and contains one WD repeat, playing a crucial role in cellular processes due to involvement in regulatory mechanisms such as chromatin assembly, cell cycle control, and signal transduction. The presence of WD repeats, characterized by a conserved core of 40-60 amino acids that typically form a tertiary propeller structure, allows WDR93 to interact with various partners, facilitating complex cellular functions. WDR93 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 15, a region associated with several genetic disorders, including Angelman syndrome and Prader-Willi syndrome. WDR93′s participation in diverse cellular activities underscores its importance in maintaining cellular homeostasis and highlights potential as a target for therapeutic interventions in diseases linked to chromosomal abnormalities.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
WDR93 Antibody (A-5) References:
- The WD repeat: a common architecture for diverse functions. | Smith, TF., et al. 1999. Trends Biochem Sci. 24: 181-5. PMID: 10322433
- The WD-40 repeat. | van der Voorn, L. and Ploegh, HL. 1992. FEBS Lett. 307: 131-4. PMID: 1644165
- Diagnosis and management of patients with Marfan syndrome. | Midla, GS. 2008. JAAPA. 21: 21-5. PMID: 18323350
- Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteins. | Hudson, AM. and Cooley, L. 2008. Subcell Biochem. 48: 6-19. PMID: 18925367
- The C15orf2 gene in the Prader-Willi syndrome region is subject to genomic imprinting and positive selection. | Wawrzik, M., et al. 2010. Neurogenetics. 11: 153-61. PMID: 20020165
- Tyrosinemia type 1 and Angelman syndrome due to paternal uniparental isodisomy 15. | Ferrer-Bolufer, I., et al. 2009. J Inherit Metab Dis. 32 Suppl 1: S349-53. PMID: 20033293
- The ancient regulatory-protein family of WD-repeat proteins. | Neer, EJ., et al. 1994. Nature. 371: 297-300. PMID: 8090199
- Neuropsychiatric aspects of adult-onset Tay-Sachs disease: two case reports with several new findings. | Hurowitz, GI., et al. 1993. J Neuropsychiatry Clin Neurosci. 5: 30-6. PMID: 8428133
- Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit. | Garcia-Higuera, I., et al. 1996. Biochemistry. 35: 13985-94. PMID: 8909296
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR93 Antibody (A-5) | sc-393763 | 200 µg/ml | $322.00 | |||
WDR93 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-526265 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR93 Antibody (A-5): m-IgG2a BP-HRP Bundle | sc-546547 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR93 Antibody (A-5) AC | sc-393763 AC | 500 µg/ml, 25% agarose | $424.00 | |||
WDR93 Antibody (A-5) HRP | sc-393763 HRP | 200 µg/ml | $322.00 | |||
WDR93 Antibody (A-5) FITC | sc-393763 FITC | 200 µg/ml | $336.00 | |||
WDR93 Antibody (A-5) PE | sc-393763 PE | 200 µg/ml | $349.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 488 | sc-393763 AF488 | 200 µg/ml | $364.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 546 | sc-393763 AF546 | 200 µg/ml | $364.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 594 | sc-393763 AF594 | 200 µg/ml | $364.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 647 | sc-393763 AF647 | 200 µg/ml | $364.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 680 | sc-393763 AF680 | 200 µg/ml | $364.00 | |||
WDR93 Antibody (A-5) Alexa Fluor® 790 | sc-393763 AF790 | 200 µg/ml | $364.00 | |||
WDR93 (A-5) Neutralizing Peptide | sc-393763 P | 100 µg/0.5 ml | $69.00 |