WDR92 Antibody (D-4): sc-393131
- WDR92 Antibody (D-4) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 307-335 near the C-terminus of WDR92 of human origin
- recommended for detection of WDR92 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, porcine and avian
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for WDR92 Antibody (D-4) for WB applications. These reagents are now offered in bundles with WDR92 Antibody (D-4) (see ordering information below).
WDR92 Antibody (D-4) is a mouse monoclonal IgG2a antibody that detects WDR92 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). WDR92, also known as WD repeat-containing protein Monad, is a 357 amino acid protein characterized by the presence of six WD-repeats, which are motifs that typically form a tertiary propeller structure. This unique structure allows WDR92 to participate in various cellular functions, particularly in the regulation of apoptosis, a vital process for maintaining cellular homeostasis and preventing uncontrolled cell proliferation. WDR92 expression is notably highest in the testis, indicating a potential role in reproductive biology. Furthermore, the gene encoding WDR92 is located on human chromosome 2, a region associated with numerous genetic diseases, including Harlequin ichthyosis and Alström syndrome, highlighting WDR92′s importance in both normal physiology and disease states. Anti-WDR92 antibody (D-4) serves as an essential tool for researchers investigating the intricate roles of WD-repeat proteins in cellular regulation and their implications in health and disease.
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WDR92 Antibody (D-4) References:
- Discovery of a dicer-independent, cell-type dependent alternate targeting sequence generator: implications in gene silencing & pooled RNAi screens. | Bhinder, B., et al. 2014. PLoS One. 9: e100676. PMID: 24987961
- Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP. | Zur Lage, P., et al. 2018. J Cell Biol. 217: 2583-2598. PMID: 29743191
- Genetic variants in fat- and short-tailed sheep from high-throughput RNA-sequencing data. | Ma, L., et al. 2018. Anim Genet. 49: 483-487. PMID: 30069889
- Chlamydomonas WDR92 in association with R2TP-like complex and multiple DNAAFs to regulate ciliary dynein preassembly. | Liu, G., et al. 2019. J Mol Cell Biol. 11: 770-780. PMID: 30428028
- The Multiple Functions of the PAQosome: An R2TP- and URI1 Prefoldin-Based Chaperone Complex. | Lynham, J. and Houry, WA. 2018. Adv Exp Med Biol. 1106: 37-72. PMID: 30484152
- WDR92 is required for axonemal dynein heavy chain stability in cytoplasm. | Patel-King, RS., et al. 2019. Mol Biol Cell. 30: 1834-1845. PMID: 31116681
- Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. | Singh, S., et al. 2019. Sci Rep. 9: 17323. PMID: 31754133
- Role of the Novel Hsp90 Co-Chaperones in Dynein Arms' Preassembly. | Fabczak, H. and Osinka, A. 2019. Int J Mol Sci. 20: PMID: 31817850
- Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism. | Metzendorf, C., et al. 2020. Molecules. 25: PMID: 32927708
- Integrative analysis prioritizes the relevant genes and risk factors for chronic venous disease. | He, R., et al. 2022. J Vasc Surg Venous Lymphat Disord. 10: 738-748.e5. PMID: 35218958
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR92 Antibody (D-4) | sc-393131 | 200 µg/ml | $322.00 | |||
WDR92 Antibody (D-4): m-IgG Fc BP-HRP Bundle | sc-538148 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR92 Antibody (D-4): m-IgGκ BP-HRP Bundle | sc-535708 | 200 µg Ab; 40 µg BP | $361.00 | |||
WDR92 Antibody (D-4): m-IgG2a BP-HRP Bundle | sc-548217 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR92 (D-4) Neutralizing Peptide | sc-393131 P | 100 µg/0.5 ml | $69.00 |