WASP Antibody (B-12): sc-398477
- WASP Antibody (B-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 21-48 near the N-terminus of WASP of human origin
- recommended for detection of WASP of mouse, rat and human origin by WB, IP, IF and ELISA
- See WASP (B-9): sc-13139 for WASP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for WASP Antibody (B-12) for WB applications. This reagent is now offered in a bundle with WASP Antibody (B-12) (see ordering information below).
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SEE ALSO...
WASP Antibody (B-12) is a mouse monoclonal IgG1 antibody that detects WASP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). WASP, or Wiskott-Aldrich syndrome protein, plays a crucial role in the regulation of the actin cytoskeleton, which is essential for various cellular processes, including cell shape, motility, and division. The proper functioning of WASP is particularly important in immune cells, where WASP facilitates the formation of actin-rich structures necessary for effective immune responses. Mutations in the WASP gene lead to the Wiskott-Aldrich syndrome, characterized by immunodeficiency and increased susceptibility to infections, highlighting WASP′s vital role in maintaining immune system integrity. WASP (B-12) antibody contains a unique structure that includes a Cdc42/Rac interacting domain, which is critical for WASP′s function as a downstream effector of Cdc42, a small GTPase involved in cytoskeletal dynamics. By utilizing anti-WASP antibody (B-12), researchers can gain insights into WASP′s involvement in cytoskeletal organization and implications in various diseases, making WASP (B-12) antibody an invaluable tool for studying the underlying mechanisms of Wiskott-Aldrich syndrome and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WASP Antibody (B-12) | sc-398477 | 200 µg/ml | $322.00 | |||
WASP Antibody (B-12): m-IgG Fc BP-HRP Bundle | sc-540935 | 200 µg Ab; 10 µg BP | $361.00 | |||
WASP (B-12) Neutralizing Peptide | sc-398477 P | 100 µg/0.5 ml | $69.00 |