Vimentin siRNA and shRNA Plasmids (m) mouse Vimentin-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

Vimentin siRNA and shRNA Plasmids (m)

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    • Target species: mouse; for corresponding human product, see Vimentin siRNA and shRNA Plasmids (h)
    • Gene Silencers generally consist of pools of three to five target-specific 19-25 nucleotide sequences in length
    • For independent verification of Vimentin gene silencing results, individual duplex components or plasmids are also available upon request
    • Suitable control antibody: Vimentin Antibody (E-5): sc-373717 is recommended as control antibody for monitoring of Vimentin expression knockdown by Western blotting or immunofluorescence
    • For further details describing the si/shRNA Gene Silencers click here
    • Gene silencers are intended for noncommercial and research use only. Click here for details.
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Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
MouseVim223522 A1NM_011701P20152N/A

Has this shRNA been validated for its knockdown ability? It's alot of money to spend without knowing if it has been validated before.

Asked by: Darcie
Thank you for your question. Our mouse Vimentin siRNA (sc-29523) has been published previously, demonstrating knockdown specificity of the targeting sequences of this RNAi reagent. Please refer to the following journal articles as a reference (PMID's: 25787077 and 26773517). Santa Cruz does warranty our si/shRNA reagents to show observable knockdown at the protein level.  Santa Cruz implements computationally designed published algorithms which are demonstrated to give greater than 50% knockdown more than 90% of the time. If you purchase the reagents and are not able to achieve the expected results we encourage you to contact our Technical Support staff.  If we are unable to trouble-shoot the assay further then we are able to offer you either research credit or refund the purchase price of the reagents.
Answered by: Technical Support
Date published: 2017-01-23
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