VEGF-C Antibody (MM0006-2E65) is a mouse monoclonal IgG2 antibody that detects vascular endothelial growth factor C (VEGF-C) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. VEGF-C plays a crucial role in lymphangiogenesis, the formation of lymphatic vessels, which is essential for maintaining fluid homeostasis and immune responses in tissues. VEGF-C is primarily located in the extracellular space and is secreted by various cell types, including endothelial cells and fibroblasts. Proper localization of VEGF-C is vital, as VEGF-C interacts with specific receptors such as Flt-4, which mediates effects on lymphatic endothelial cells, promoting their proliferation and migration. Dysregulation of VEGF-C signaling has been implicated in several pathological conditions, including cancer metastasis and lymphedema, making VEGF-C a significant target for therapeutic interventions. Anti-VEGF-C antibody (MM0006-2E65) is an invaluable tool for researchers studying the mechanisms of angiogenesis and lymphangiogenesis, as well as their implications in disease progression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEGF-C Antibody (MM0006-2E65) | sc-101583 | 100 µg/ml | $316.00 |