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VEGF-C Antibody (F-5): sc-398004

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Datasheets
  • VEGF-C Antibody (F-5) is a mouse monoclonal IgM κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 29-52 near the N-terminus of VEGF-C of human origin
  • recommended for detection of VEGF-C precursor of mouse, rat and human origin by WB, IP, IF and ELISA
  • See VEGF-C (E-6): sc-374628 for VEGF-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for VEGF-C Antibody (F-5). This work is in progress.

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    VEGF-C Antibody (F-5) is a mouse monoclonal IgM antibody that detects VEGF-C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). VEGF-C is a crucial member of the vascular endothelial growth factor family, primarily known for its role in lymphangiogenesis, the formation of lymphatic vessels, which is essential for maintaining fluid homeostasis and immune responses. VEGF-C is predominantly expressed in lymphatic endothelial cells and plays a significant role in promoting the growth and survival of these cells. Importantly, VEGF-C interacts with specific receptors, such as Flt-4 and Flk-1, which are vital for mediating effects on vascular permeability and endothelial cell proliferation. Dysregulation of VEGF-C signaling has been implicated in various pathological conditions, including cancer metastasis and lymphedema, making VEGF-C a critical target for therapeutic intervention. anti-VEGF-C antibody (F-5) provides a reliable tool for researchers investigating the complex mechanisms of angiogenesis and lymphangiogenesis, contributing to a deeper understanding of these processes in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    VEGF-C Antibody (F-5)

    sc-398004
    200 µg/ml
    $316.00

    VEGF-C (F-5) Neutralizing Peptide

    sc-398004 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-398004 P appropriate for?

    Asked by: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
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    Rated 4 out of 5 by from Works with human VEGFWorks with human VEGF-C transfected 293T and MH-S whole cell lysates. -SCBT QC
    Date published: 2013-08-29
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    VEGF-C Antibody (F-5) is rated 4.0 out of 5 by 1.
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