VDUP1 Antibody (D-2): sc-271237
- VDUP1 Antibody (D-2) is a mouse monoclonal IgG1 κ VDUP1 antibody, cited in 14 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 342-370 at the C-terminus of VDUP1 of human origin
- VDUP1 Antibody (D-2) is recommended for detection of VDUP1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-VDUP1 Antibody (D-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for VDUP1 Antibody (D-2) for WB applications. This reagent is now offered in a bundle with VDUP1 Antibody (D-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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SEE ALSO...
VDUP1 Antibody (D-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects VDUP1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). VDUP1 (D-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. VDUP1, also known as thioredoxin interacting protein, plays a crucial role in cellular stress responses, being upregulated by 1,25(OH)2D3 in reaction to oxidative stress, ultraviolet radiation, and heat shock. VDUP1 acts as a natural antagonist of thioredoxin, contributing to tumor suppression by inducing cell cycle arrest at the G0/G1 phase, which is vital for preventing uncontrolled cell proliferation. Additionally, VDUP1 is essential for the expression of CD122 and the maturation of natural killer (NK) cells, although VDUP1 has a minimal impact on T and B cell development. The gene encoding human VDUP1 is located on chromosome 1q21, and VDUP1 is ubiquitously expressed across various tissues, predominantly localizing in the cytoplasm. Given VDUP1′s significant role in immune regulation and potential as a therapeutic target for melanoma, VDUP1 continues to be an important focus of research in cancer biology and immunology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VDUP1 Antibody (D-2) | sc-271237 | 200 µg/ml | $322.00 | |||
VDUP1 Antibody (D-2): m-IgGκ BP-HRP Bundle | sc-521887 | 200 µg Ab, 40 µg BP | $361.00 | |||
VDUP1 Antibody (D-2) AC | sc-271237 AC | 500 µg/ml, 25% agarose | $424.00 | |||
VDUP1 Antibody (D-2) HRP | sc-271237 HRP | 200 µg/ml | $322.00 | |||
VDUP1 Antibody (D-2) FITC | sc-271237 FITC | 200 µg/ml | $336.00 | |||
VDUP1 Antibody (D-2) PE | sc-271237 PE | 200 µg/ml | $349.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 488 | sc-271237 AF488 | 200 µg/ml | $364.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 546 | sc-271237 AF546 | 200 µg/ml | $364.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 594 | sc-271237 AF594 | 200 µg/ml | $364.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 647 | sc-271237 AF647 | 200 µg/ml | $364.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 680 | sc-271237 AF680 | 200 µg/ml | $364.00 | |||
VDUP1 Antibody (D-2) Alexa Fluor® 790 | sc-271237 AF790 | 200 µg/ml | $364.00 | |||
VDUP1 (D-2) Neutralizing Peptide | sc-271237 P | 100 µg/0.5 ml | $69.00 |