Vascular Endothelium Antibody (10): sc-53461

Vascular Endothelium Antibody (10) is a mouse monoclonal IgM kappa light chain antibody that detects Vascular Endothelium protein of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Vascular Endothelium antibody (10) is available as a non-conjugated format. Vascular Endothelium protein plays a crucial role in maintaining vascular homeostasis, influencing vascular tone, hemostasis, and immune response. Vascular Endothelium protein is primarily located on the inner lining of blood vessels, acting as a selective barrier between circulating blood and surrounding tissues, facilitating the exchange of nutrients and waste products. Maintaining endothelial layer integrity prevents vascular leakage and maintains blood flow, while dysfunction can lead to various cardiovascular diseases. Vascular Endothelium protein regulates smooth muscle function and modulates leukocyte and platelet adhesion, essential for inflammatory responses and wound healing. Anti-Vascular Endothelium antibody (10) serves as an invaluable tool for researchers studying endothelial biology and its implications in health and disease.

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Vascular Endothelium Antibody (10) References:

1. [Vascular endothelium: target organ of cardiovascular pathologies].  |  Berkenboom, G. 1999. Ann Cardiol Angeiol (Paris). 48: 643-6. PMID: 12555471
2. Morphological changes in hepatic vascular endothelium after carbon dioxide pneumoperitoneum in a murine model.  |  Izumi, K., et al. 2005. Surg Endosc. 19: 554-8. PMID: 15696359
3. Endogenous L-glutamate transport in oocytes of Xenopus laevis.  |  Steffgen, J., et al. 1991. Biochim Biophys Acta. 1066: 14-20. PMID: 1676599
4. Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium.  |  Gong, R., et al. 2006. J Am Soc Nephrol. 17: 2464-73. PMID: 16885407
5. Myeloid lineage progenitors give rise to vascular endothelium.  |  Bailey, AS., et al. 2006. Proc Natl Acad Sci U S A. 103: 13156-61. PMID: 16920790
6. Eicosanoids and the vascular endothelium.  |  Egan, K. and FitzGerald, GA. 2006. Handb Exp Pharmacol. 189-211. PMID: 16999220
7. Nitric oxide and the vascular endothelium.  |  Moncada, S. and Higgs, EA. 2006. Handb Exp Pharmacol. 213-54. PMID: 16999221
8. Vascular endothelium and blood flow.  |  Busse, R. and Fleming, I. 2006. Handb Exp Pharmacol. 43-78. PMID: 16999224
9. Features of synovial membrane identified with monoclonal antibodies.  |  Palmer, DG., et al. 1985. Clin Exp Immunol. 59: 529-38. PMID: 3886218

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Vascular Endothelium Antibody (10) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Vascular Endothelium Antibody (10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Vascular Endothelium Antibody (10) Specifications

Alternate Product Name: Vascular Endothelium

Product Clone Name: 10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: Vascular Endothelium

Epitope Species: human

Product Reactivity/Detection: Vascular Endothelium

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Vascular Endothelium Antibody (10): N/A