Varicella Zoster Virus gpIII Antibody (SG3): sc-58075

Varicella Zoster Virus gpIII Antibody (SG3) is a mouse monoclonal IgG1 antibody that detects Varicella Zoster Virus gpIII protein in non-species reactive applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Varicella Zoster Virus gpIII antibody (SG3) is available as a non-conjugated format. The Varicella Zoster Virus, commonly referred to as VZV, is responsible for two significant diseases: childhood chickenpox (varicella) and shingles (zoster). Varicella Zoster Virus gpIII protein plays a vital role in viral infection of host cells and immune response evasion. Varicella Zoster Virus gpIII (SG3) antibody recognizes this glycoprotein, which is integral to the virus′s envelope and facilitates entry into host cells by mediating membrane fusion. This structural component enables efficient assembly and release of viral particles. Varicella Zoster Virus gpIII protein interacts with other viral proteins, such as glycoprotein E (gE), which is critical for viral envelope formation and virus spread within the host. Post-translational modifications, such as glycosylation, enhance Varicella Zoster Virus gpIII functionality and stability, making this protein a key target for therapeutic interventions and vaccine development.

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Varicella Zoster Virus gpIII Antibody (SG3) References:

1. Transcription factor Sp1 is involved in the regulation of varicella-zoster virus glycoprotein E.  |  Rahaus, M. and Wolff, MH. 2000. Virus Res. 69: 69-81. PMID: 10989187
2. Essential role played by the C-terminal domain of glycoprotein I in envelopment of varicella-zoster virus in the trans-Golgi network: interactions of glycoproteins with tegument.  |  Wang, ZH., et al. 2001. J Virol. 75: 323-40. PMID: 11119602
3. Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates.  |  Kleinschmidt-DeMasters, BK. and Gilden, DH. 2001. Arch Pathol Lab Med. 125: 770-80. PMID: 11371229
4. Varicella-zoster virus glycoproteins E and I expressed in insect cells form a heterodimer that requires the N-terminal domain of glycoprotein I.  |  Kimura, H., et al. 1997. Virology. 233: 382-91. PMID: 9217061
5. Varicella-zoster virus glycoprotein I is essential for growth of virus in Vero cells.  |  Cohen, JI. and Nguyen, H. 1997. J Virol. 71: 6913-20. PMID: 9261418
6. Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking.  |  Mallory, S., et al. 1997. J Virol. 71: 8279-88. PMID: 9343180

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Varicella Zoster Virus gpIII Antibody (SG3) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Varicella Zoster Virus gpIII Antibody (SG3) Specifications

Alternate Product Name: Varicella Zoster Virus gpIII

Product Clone Name: SG3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Varicella Zoster Virus gpIII

Epitope Species: Varicella Zoster virus, Ellen strain

Product Reactivity/Detection: Varicella Zoster Virus Ellen strain

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Varicella Zoster Virus gpIII Antibody (SG3): N/A