utrophin Antibody (7F3): sc-81556
- utrophin Antibody (7F3) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against a fusion protien containing amino acids 3104-3433 mapping to the C-terminus of utrophin of human origin
- Anti-utrophin Antibody (7F3) is recommended for detection of utrophin of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-utrophin Antibody (7F3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for utrophin Antibody (7F3). This work is in progress.
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SEE ALSO...
utrophin Antibody (7F3) is a mouse monoclonal IgG2a kappa light chain antibody that detects utrophin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. anti-utrophin antibody (7F3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Utrophin plays a crucial role in muscle function and cellular integrity, as utrophin is a structural, actin-binding protein that helps anchor the cytoskeleton to the plasma membrane, similar to dystrophin, which is associated with Duchenne and Becker muscular dystrophies. Utrophin is primarily localized to the inner surface of the plasma membrane in muscle and brain tissues, where utrophin is essential for maintaining the stability of muscle fibers during contraction. Alternative splicing of utrophin allows interaction with various proteins, which is vital for function in muscle tissue. Upregulation of utrophin has been shown to mitigate the effects of dystrophic pathology, making utrophin a potential therapeutic target for muscular dystrophies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
utrophin Antibody (7F3) | sc-81556 | 200 µg/ml | $322.00 | |||
utrophin Antibody (7F3) AC | sc-81556 AC | 500 µg/ml, 25% agarose | $424.00 | |||
utrophin Antibody (7F3) HRP | sc-81556 HRP | 200 µg/ml | $322.00 | |||
utrophin Antibody (7F3) FITC | sc-81556 FITC | 200 µg/ml | $336.00 | |||
utrophin Antibody (7F3) PE | sc-81556 PE | 200 µg/ml | $349.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 488 | sc-81556 AF488 | 200 µg/ml | $364.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 546 | sc-81556 AF546 | 200 µg/ml | $364.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 594 | sc-81556 AF594 | 200 µg/ml | $364.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 647 | sc-81556 AF647 | 200 µg/ml | $364.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 680 | sc-81556 AF680 | 200 µg/ml | $364.00 | |||
utrophin Antibody (7F3) Alexa Fluor® 790 | sc-81556 AF790 | 200 µg/ml | $364.00 |