urotensin II Antibody (UII-6): sc-52300
- urotensin II Antibody (UII-6) is a mouse monoclonal IgG provided at 100 µg/ml
- raised against human urotensin II
- recommended for detection of urotensin II of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for urotensin II Antibody (UII-6). This work is in progress.
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Urotensin II Antibody (UII-6) is a mouse monoclonal IgG antibody that detects Urotensin II in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Urotensin II is a potent vasoactive peptide that plays a crucial role in cardiovascular regulation, primarily by inducing vasoconstriction and influencing blood pressure. This peptide is synthesized in various tissues, including vascular and cardiac tissues, where Urotensin II is involved in autocrine and paracrine signaling mechanisms. Notably, Urotensin II interacts with the G protein-coupled receptor GPR14, which mediates biological effects. The cyclic structure of Urotensin II, conserved across species, is essential for activity, highlighting the evolutionary significance of this peptide in maintaining cardiovascular homeostasis. Furthermore, Urotensin II has been implicated in pathological conditions such as ventricular hypertrophy, particularly in response to chronic hypoxia, making Urotensin II a critical target for research in cardiovascular diseases. Anti-Urotensin II antibody (UII-6) is an invaluable tool for studying this peptide in various physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
urotensin II Antibody (UII-6) | sc-52300 | 100 µg/ml | $322.00 |