UBE2S Antibody (F-10): sc-398339
- UBE2S Antibody (F-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-22 at the N-terminus of UBE2S of human origin
- recommended for detection of UBE2S of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for UBE2S Antibody (F-10) for WB applications. This reagent is now offered in a bundle with UBE2S Antibody (F-10) (see ordering information below).
UBE2S Antibody (F-10) is a mouse monoclonal IgG1 antibody that detects UBE2S in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UBE2S, also known as EPF5 or E2EPF, is a 222 amino acid protein that plays a crucial role in the ubiquitin-proteasome pathway, which is essential for regulating protein degradation within the cell. UBE2S is primarily located in the cytoplasm, where UBE2S facilitates the attachment of ubiquitin to target proteins, marking them for degradation by the proteasome. Proper functioning of UBE2S is vital, as dysregulation of this process can lead to the accumulation of abnormal proteins, contributing to various diseases, including cancer. UBE2S has been implicated in enhancing tumor cell proliferation, invasion, and metastasis through interactions with the von Hippel-Lindau (VHL) pathway, highlighting UBE2S significance in carcinogenesis. With an ability to provide insights into the mechanisms of protein degradation and potential role in cancer progression, anti-UBE2S antibody (F-10) is an invaluable tool for researchers studying cellular regulation and disease pathology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE2S Antibody (F-10) | sc-398339 | 200 µg/ml | $322.00 | |||
UBE2S Antibody (F-10): m-IgG Fc BP-HRP Bundle | sc-540934 | 200 µg Ab; 10 µg BP | $361.00 | |||
UBE2S (F-10) Neutralizing Peptide | sc-398339 P | 100 µg/0.5 ml | $69.00 |