UBE2J1 Antibody (18-Y): sc-100624
- UBE2J1 Antibody (18-Y) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 100 µg/ml
- raised against recombinant UBE2J1 of human origin
- recommended for detection of UBE2J1 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for UBE2J1 Antibody (18-Y). This work is in progress.
UBE2J1 Antibody (18-Y) is a mouse monoclonal IgG2a antibody that detects UBE2J1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). UBE2J1, also known as Ubc6p, CGI-76, NCUBE1, HSPC153, or HSPC205, is a crucial component of the ubiquitin-proteasome system, which plays a vital role in maintaining cellular homeostasis by regulating protein degradation. This 318 amino acid single-pass type IV membrane protein is localized to the endoplasmic reticulum (ER) membrane, where UBE2J1 facilitates the attachment of ubiquitin to misfolded or damaged membrane proteins, marking them for proteasomal degradation. This process is essential for quality control within the ER, as UBE2J1 prevents the accumulation of dysfunctional proteins that could disrupt cellular function. UBE2J1′s activity is ATP-dependent, resulting in the production of AMP, a diphosphate, and a ubiquitin-tagged protein, underscoring UBE2J1′s importance in cellular health and the prevention of diseases associated with protein misfolding. Anti-UBE2J1 antibody (18-Y) is an invaluable tool for researchers studying the mechanisms of protein degradation and the role of ubiquitination in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE2J1 Antibody (18-Y) | sc-100624 | 100 µg/ml | $333.00 |