UBE2G1 Antibody (H-2): sc-398969
- UBE2G1 Antibody (H-2) is a mouse monoclonal IgG1 κ UBE2G1 antibody provided at 200 µg/ml
- raised against amino acids 1-50 mapping at the N-terminus of UBE2G1 of human origin
- UBE2G1 Antibody (H-2) is recommended for detection of UBE2G1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-UBE2G1 Antibody (H-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for UBE2G1 Antibody (H-2) for WB applications. These reagents are now offered in bundles with UBE2G1 Antibody (H-2) (see ordering information below).
UBE2G1 Antibody (H-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects UBE2G1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UBE2G1 Antibody (H-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. UBE2G1 plays a crucial role in the ubiquitin-proteasome system, which maintains cellular homeostasis by regulating protein degradation. UBE2G1 is primarily located in the cytoplasm, where UBE2G1 facilitates the transfer of ubiquitin to target proteins, marking them for degradation. Proper functioning of UBE2G1 helps eliminate damaged or misfolded proteins, preventing accumulation of potentially toxic proteins that could disrupt cellular functions. UBE2G1 interacts with various E3 ligases, which recognize specific substrates for ubiquitination, further underscoring UBE2G1′s importance in cellular regulation and signaling pathways. UBE2G1′s ability to mediate these processes highlights UBE2G1′s significance in cellular health and potential implications in diseases where protein misfolding and degradation are involved.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
UBE2G1 Antibody (H-2) References:
- Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. | Gong, L. and Yeh, ET. 1999. J Biol Chem. 274: 12036-42. PMID: 10207026
- Heat-induced cell cycle arrest of Saccharomyces cerevisiae: involvement of the RAD6/UBC2 and WSC2 genes in its reversal. | Raboy, B., et al. 1999. Mol Microbiol. 32: 729-39. PMID: 10361277
- SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4. | Strack, P., et al. 2000. Oncogene. 19: 3529-36. PMID: 10918611
- Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. | Hochstrasser, M. 1995. Curr Opin Cell Biol. 7: 215-23. PMID: 7612274
- The ubiquitin-proteasome proteolytic pathway. | Ciechanover, A. 1994. Cell. 79: 13-21. PMID: 7923371
- The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins. | Ciechanover, A. and Schwartz, AL. 1994. FASEB J. 8: 182-91. PMID: 8119489
- The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme. | Schwarz, SE., et al. 1998. Proc Natl Acad Sci U S A. 95: 560-4. PMID: 9435231
- A novel protein modification pathway related to the ubiquitin system. | Liakopoulos, D., et al. 1998. EMBO J. 17: 2208-14. PMID: 9545234
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE2G1 Antibody (H-2) | sc-398969 | 200 µg/ml | $322.00 | |||
UBE2G1 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-527837 | 200 µg Ab; 10 µg BP | $361.00 | |||
UBE2G1 Antibody (H-2): m-IgG1 BP-HRP Bundle | sc-533210 | 200 µg Ab; 20 µg BP | $361.00 | |||
UBE2G1 Antibody (H-2) AC | sc-398969 AC | 500 µg/ml, 25% agarose | $424.00 | |||
UBE2G1 Antibody (H-2) HRP | sc-398969 HRP | 200 µg/ml | $322.00 | |||
UBE2G1 Antibody (H-2) FITC | sc-398969 FITC | 200 µg/ml | $336.00 | |||
UBE2G1 Antibody (H-2) PE | sc-398969 PE | 200 µg/ml | $349.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 488 | sc-398969 AF488 | 200 µg/ml | $364.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 546 | sc-398969 AF546 | 200 µg/ml | $364.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 594 | sc-398969 AF594 | 200 µg/ml | $364.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 647 | sc-398969 AF647 | 200 µg/ml | $364.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 680 | sc-398969 AF680 | 200 µg/ml | $364.00 | |||
UBE2G1 Antibody (H-2) Alexa Fluor® 790 | sc-398969 AF790 | 200 µg/ml | $364.00 |