UBE1L Antibody (B-7): sc-390097
- UBE1L Antibody (B-7) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 299-337 within an internal region of UBE1L of human origin
- Anti-UBE1L Antibody (B-7) is recommended for detection of UBE1L of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-UBE1L Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for UBE1L Antibody (B-7) for WB applications. These reagents are now offered in bundles with UBE1L Antibody (B-7) (see ordering information below).
UBE1L Antibody (B-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects UBE1L in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-UBE1L antibody (B-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. UBE1L, or Ubiquitin-activating enzyme E1 homolog, plays a crucial role in the ubiquitin-proteasome system, which is essential for regulating protein degradation and maintaining cellular homeostasis. UBE1L is involved in the activation of ubiquitin through an ATP-dependent adenylation process, where UBE1L first adenylates ubiquitin and then forms a thioester bond with a cysteine residue, facilitating the transfer of ubiquitin to target proteins. UBE1L expression in tumor cells acts as a retinoid target that, through conjugation with ISG15 (Interferon-induced 15 kDa protein), can trigger degradation and apoptosis in acute promyelocytic leukemia. UBE1L′s ability to regulate protein turnover and involvement in critical cellular processes make UBE1L a significant target for research in cancer biology and therapeutic development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE1L Antibody (B-7) | sc-390097 | 200 µg/ml | $316.00 | |||
UBE1L Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-523400 | 200 µg Ab, 40 µg BP | $354.00 | |||
UBE1L Antibody (B-7): m-IgG1 BP-HRP Bundle | sc-533578 | 200 µg Ab; 20 µg BP | $354.00 | |||
UBE1L Antibody (B-7) AC | sc-390097 AC | 500 µg/ml, 25% agarose | $416.00 | |||
UBE1L Antibody (B-7) HRP | sc-390097 HRP | 200 µg/ml | $316.00 | |||
UBE1L Antibody (B-7) FITC | sc-390097 FITC | 200 µg/ml | $330.00 | |||
UBE1L Antibody (B-7) PE | sc-390097 PE | 200 µg/ml | $343.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 488 | sc-390097 AF488 | 200 µg/ml | $357.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 546 | sc-390097 AF546 | 200 µg/ml | $357.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 594 | sc-390097 AF594 | 200 µg/ml | $357.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 647 | sc-390097 AF647 | 200 µg/ml | $357.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 680 | sc-390097 AF680 | 200 µg/ml | $357.00 | |||
UBE1L Antibody (B-7) Alexa Fluor® 790 | sc-390097 AF790 | 200 µg/ml | $357.00 | |||
UBE1L (B-7) Neutralizing Peptide | sc-390097 P | 100 µg/0.5 ml | $68.00 |