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TUSC3 Antibody (D-9): sc-390566

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Datasheets
  • TUSC3 Antibody (D-9) is a mouse monoclonal IgM κ TUSC3 antibody, cited in 2 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 96-115 of TUSC3 of human origin
  • recommended for detection of TUSC3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and porcine
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TUSC3 Antibody (D-9). This work is in progress.

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TUSC3 Antibody (D-9) is a mouse monoclonal IgM antibody that detects TUSC3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TUSC3 antibody (D-9) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. TUSC3, or Tumor Suppressor Candidate 3, plays a critical role in cellular processes, particularly in regulating protein glycosylation, which is essential for proper protein folding and stability. This function is vital as aberrations in glycosylation can lead to various diseases, including cancer and congenital disorders. TUSC3 is located in the endoplasmic reticulum, where TUSC3 is involved in glycoprotein synthesis, and TUSC3 dysfunction can disrupt normal cellular signaling pathways, contributing to tumorigenesis. Understanding TUSC3 and cellular interactions can provide insights into potential therapeutic targets for treating related diseases.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

TUSC3 Antibody (D-9) References:

  1. Chromosomes 8 and 10 workshop.  |  Wildenauer, DB. and Schwab, SG. 1999. Am J Med Genet. 88: 239-43. PMID: 10374738
  2. Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced.  |  Kashino, G., et al. 2001. Biochem Biophys Res Commun. 289: 111-5. PMID: 11708785
  3. Cytogenetic mapping of a novel locus for type II Waardenburg syndrome.  |  Selicorni, A., et al. 2002. Hum Genet. 110: 64-7. PMID: 11810298
  4. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.  |  McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
  5. DNA sequence and analysis of human chromosome 8.  |  Nusbaum, C., et al. 2006. Nature. 439: 331-5. PMID: 16421571
  6. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.  |  Agrelo, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8822-7. PMID: 16723399
  7. Non-Hodgkin's lymphomas with Burkitt-like cells are associated with c-Myc amplification and poor prognosis.  |  Mossafa, H., et al. 2006. Leuk Lymphoma. 47: 1885-93. PMID: 17065002

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TUSC3 Antibody (D-9)

sc-390566
200 µg/ml
$316.00

TUSC3 (D-9) Neutralizing Peptide

sc-390566 P
100 µg/0.5 ml
$68.00

We are going to purchase sc-390566 antibody for WB. As recommended, we are also purchasing sc-516102, sc-2048, and sc-516214. Does sc-516102 will serve the purpose of both secondary Ab and marker? Do we need to buy anything else for our WB experiment.

Asked by: Asmat
Thank you for the question. Regarding the mol. weight marker for the Western Blot experiment we suggest using our Cruz Marker™ sc-2035 together with our Cruz Marker™ compatible -HRP conjugated mouse IgG kappa binding protein, m-IgGκ BP-HRP sc-516102-CM. https://datasheets.scbt.com/sc-516102-CM.pdf If you prefer using Pre-staining markers instead we suggest using our Broad Range Markers sc-2361 with the sc-516102 mentioned in your original inquiry.
Answered by: Technical Support Europe
Date published: 2018-01-31

What application is the blocking peptide sc-390566 P appropriate for?

Asked by: Randy McDonald
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
  • y_2025, m_10, d_15, h_8CST
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Rated 5 out of 5 by from Antibody with high specificityExcellent antibody in WB at 1:1000. Antibody with high specificity can be used for further experiments.
Date published: 2017-11-23
Rated 5 out of 5 by from good for western blotThis antibody for WB, the band is very clear, result is very satisfactory.
Date published: 2017-09-07
Rated 5 out of 5 by from Produced positive Western blot data of TUSC3Produced positive Western blot data of TUSC3 expression in SK-BR-3 whole cell lysate. -SCBT QC
Date published: 2013-07-01
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TUSC3 Antibody (D-9) is rated 5.0 out of 5 by 3.
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