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TSSK 6 Antibody (M-12) is a mouse monoclonal IgG2a antibody that detects TSSK 6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TSSK 6, also known as testis-specific serine kinase 6, SSTK, TSSK4, FKSG82, or CT72, is a 273 amino acid protein that plays a crucial role in sperm production and chromatin remodeling by catalyzing the ATP-dependent phosphorylation of target proteins. TSSK 6 is predominantly expressed in the testis, with lower levels found in the ovary, colon, thymus, small intestine, and spleen, highlighting a specialized function in male reproductive biology. A protein kinase domain within TSSK 6 utilizes magnesium as a cofactor, which is essential for enzymatic activity. Proper functioning of TSSK 6 is vital for sperm development and motility, as well as for DNA condensation processes during spermatogenesis. Defects in the gene encoding TSSK 6 have been linked to male infertility, characterized by low sperm count and reduced sperm motility, underscoring the significance in reproductive health. Anti-TSSK 6 antibody (M-12) serves as an invaluable tool for researchers studying the molecular mechanisms underlying male fertility and the regulatory pathways involving serine/threonine phosphorylation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TSSK 6 Antibody (M-12) | sc-100430 | 50 µg/0.5 ml | $339.00 |