Troponin I-SS Antibody (G-11): sc-376298

Troponin I-SS Antibody (G-11) is a mouse monoclonal IgG2a antibody that detects Troponin I in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Troponin I plays a critical role in muscle contraction by regulating the interaction between actin and myosin, which is essential for muscle function and overall movement. Troponin I is located in the thin filaments of striated muscle, where Troponin I binds to actin and inhibits the interaction with myosin in the absence of calcium. Upon calcium binding to Troponin C, Troponin I undergoes a conformational change that allows myosin to interact with actin, thus facilitating muscle contraction. The precise regulation of Troponin I is vital for maintaining proper muscle function, and dysregulation can lead to various cardiac and skeletal muscle disorders. Troponin I-SS (G-11) antibody is an invaluable tool for researchers studying muscle physiology and pathophysiology, providing insights into the mechanisms of muscle contraction and the role of calcium signaling in muscle cells.

The preferred Troponin I-SS antibody is Troponin I-SS Antibody (C-4): sc-514899.