Date published: 2025-9-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

Troponin I Antibody (C-4): sc-133117

5.0(5)
Write a reviewAsk a question

Datasheets
  • Troponin I Antibody (C-4) is a mouse monoclonal IgG2a κ, cited in 24 publications, provided at 200 µg/ml
  • raised against amino acids 40-210 mapping at the C-terminus of Troponin I-C of human origin
  • Anti-Troponin I Antibody (C-4) is recommended for detection of Troponin I, cardiac muscle; Troponin I, slow skeletal muscle; and Troponin I, fast skeletal muscle of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • Anti-Troponin I Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Troponin I (C-4): sc-133117.
  • m-IgGκ BP-HRP is the preferred secondary detection reagent for Troponin I Antibody (C-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with Troponin I Antibody (C-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.

QUICK LINKS

SEE ALSO...

Troponin I Antibody (C-4) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect Troponin I, also known as cardiac troponin I (cTnI), slow skeletal troponin I, and fast skeletal troponin I, across mouse, rat, and human species. Anti-Troponin I antibody (C-4) targets an epitope within amino acids 40-210 at the C-terminus of human Troponin I-C, ensuring precise and reliable binding for various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Troponin I is a critical component of the troponin complex, which also comprises Troponin T (cTnT) and Troponin C (cTnC), and plays a pivotal role in the regulation of muscle contraction by inhibiting actin-myosin interactions in the absence of calcium ions. Anti-Troponin I antibody (C-4) enables detailed studies of Troponin I interactions with key proteins such as actin, myosin, and other troponin subunits, which are essential for maintaining cardiac and skeletal muscle function. Additionally, Troponin I interacts with regulatory proteins like tropomyosin, further highlighting its importance in the contractile apparatus of muscle cells. Troponin I monoclonal antibody (C-4) recognition across multiple species makes this product an invaluable tool for comparative studies and translational research. Understanding the interactions and regulation of Troponin I is crucial for elucidating the mechanisms underlying muscle physiology and various pathological conditions, including myocardial infarction and muscle dystrophies. Troponin I monoclonal antibody (C-4) is an essential reagent for researchers focused on muscle contraction dynamics, cardiac biomarkers, and related disease models, offering robust performance and reliable results in investigating the complex interactions of Troponin I within the cellular environment.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Troponin I Antibody (C-4)

sc-133117
200 µg/ml
$316.00

Troponin I Antibody (C-4): m-IgGκ BP-HRP Bundle

sc-521239
200 µg Ab, 40 µg BP
$354.00

Troponin I Antibody (C-4) AC

sc-133117 AC
500 µg/ml, 25% agarose
$416.00

Troponin I Antibody (C-4) HRP

sc-133117 HRP
200 µg/ml
$316.00

Troponin I Antibody (C-4) FITC

sc-133117 FITC
200 µg/ml
$330.00

Troponin I Antibody (C-4) PE

sc-133117 PE
200 µg/ml
$343.00

Troponin I Antibody (C-4) Alexa Fluor® 488

sc-133117 AF488
200 µg/ml
$357.00

Troponin I Antibody (C-4) Alexa Fluor® 546

sc-133117 AF546
200 µg/ml
$357.00

Troponin I Antibody (C-4) Alexa Fluor® 594

sc-133117 AF594
200 µg/ml
$357.00

Troponin I Antibody (C-4) Alexa Fluor® 647

sc-133117 AF647
200 µg/ml
$357.00

Troponin I Antibody (C-4) Alexa Fluor® 680

sc-133117 AF680
200 µg/ml
$357.00

Troponin I Antibody (C-4) Alexa Fluor® 790

sc-133117 AF790
200 µg/ml
$357.00

we use this antibody (Troponin I 抗体 (C-4): sc-133117)to dectect cTnI in primary cardiomyocytes. we found this cTnI have two lands as this introduction,but we don't konw the two lands all are the cTnI or only big weight one is the cTnI

Asked by: Anonymous
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-23

How can I request for a quote? I'm interested on the # sc-133117

Asked by: Daniel Lozano
Thank you for your question. Please contact your local distributor or technical service for further assistance.
Answered by: Dallas Tech Service
Date published: 2021-06-18

What is the Kd (Dissociation constant) estimated for this antibody (sc133117)?

Asked by: CVD Biomarker
Thank you for your question. This information has not been determined for our Troponin I Antibody (C-4): sc-133117, and would have to be determined experimentally.
Answered by: Technical Support
Date published: 2017-03-01

What is the recommended secondary for this antibody?

Asked by: AbPolly
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Service
Date published: 2017-02-03
  • y_2025, m_8, d_27, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_4
  • loc_en_US, sid_133117, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 123ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Good sensitivityI used this antibody for western blot application in mouse brain samples, good results
Date published: 2023-02-02
Rated 5 out of 5 by from Very good results on mice skeletal muscle lysatesWe tested this antibody on mouse skeletal muscle lysates with very low protein inputs and were successful in detecting highly specific Troponin I signal.
Date published: 2018-04-25
Rated 5 out of 5 by from Specific antibodyWestern blot was used to rat heart tissue, the result satisfied.
Date published: 2017-05-20
Rated 5 out of 5 by from Worked in western blotWe used this antibody in a western blot with mice tissue and got a western blot band
Date published: 2016-12-27
Rated 5 out of 5 by from Very robustVery robust, positive band observed in WB (may have overloaded the gel) in mouse heart and rat heart tissue extracts. -SCBT QC
Date published: 2014-01-01
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_en_US, sid_133117, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 21ms
  • REVIEWS, PRODUCT
Troponin I Antibody (C-4) is rated 5.0 out of 5 by 5.
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_en_US, sid_133117, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 98ms
  • REVIEWS, PRODUCT