Troponin I Antibody (C-4): sc-133117
- Troponin I Antibody (C-4) is a mouse monoclonal IgG2a κ, cited in 24 publications, provided at 200 µg/ml
- raised against amino acids 40-210 mapping at the C-terminus of Troponin I-C of human origin
- Anti-Troponin I Antibody (C-4) is recommended for detection of Troponin I, cardiac muscle; Troponin I, slow skeletal muscle; and Troponin I, fast skeletal muscle of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Troponin I Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Troponin I Antibody (C-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with Troponin I Antibody (C-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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SEE ALSO...
Troponin I Antibody (C-4) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect Troponin I, also known as cardiac troponin I (cTnI), slow skeletal troponin I, and fast skeletal troponin I, across mouse, rat, and human species. Anti-Troponin I antibody (C-4) targets an epitope within amino acids 40-210 at the C-terminus of human Troponin I-C, ensuring precise and reliable binding for various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Troponin I is a critical component of the troponin complex, which also comprises Troponin T (cTnT) and Troponin C (cTnC), and plays a pivotal role in the regulation of muscle contraction by inhibiting actin-myosin interactions in the absence of calcium ions. Anti-Troponin I antibody (C-4) enables detailed studies of Troponin I interactions with key proteins such as actin, myosin, and other troponin subunits, which are essential for maintaining cardiac and skeletal muscle function. Additionally, Troponin I interacts with regulatory proteins like tropomyosin, further highlighting its importance in the contractile apparatus of muscle cells. Troponin I monoclonal antibody (C-4) recognition across multiple species makes this product an invaluable tool for comparative studies and translational research. Understanding the interactions and regulation of Troponin I is crucial for elucidating the mechanisms underlying muscle physiology and various pathological conditions, including myocardial infarction and muscle dystrophies. Troponin I monoclonal antibody (C-4) is an essential reagent for researchers focused on muscle contraction dynamics, cardiac biomarkers, and related disease models, offering robust performance and reliable results in investigating the complex interactions of Troponin I within the cellular environment.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin I Antibody (C-4) | sc-133117 | 200 µg/ml | $322.00 | |||
Troponin I Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-521239 | 200 µg Ab, 40 µg BP | $361.00 | |||
Troponin I Antibody (C-4) AC | sc-133117 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Troponin I Antibody (C-4) HRP | sc-133117 HRP | 200 µg/ml | $322.00 | |||
Troponin I Antibody (C-4) FITC | sc-133117 FITC | 200 µg/ml | $336.00 | |||
Troponin I Antibody (C-4) PE | sc-133117 PE | 200 µg/ml | $349.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 488 | sc-133117 AF488 | 200 µg/ml | $364.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 546 | sc-133117 AF546 | 200 µg/ml | $364.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 594 | sc-133117 AF594 | 200 µg/ml | $364.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 647 | sc-133117 AF647 | 200 µg/ml | $364.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 680 | sc-133117 AF680 | 200 µg/ml | $364.00 | |||
Troponin I Antibody (C-4) Alexa Fluor® 790 | sc-133117 AF790 | 200 µg/ml | $364.00 |