Troponin I Antibody (4): sc-130351

Troponin I Antibody (4) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect Troponin I, also known as cardiac troponin I (cTnI), a critical regulatory protein in cardiac muscle contraction. Anti-Troponin I antibody (4) is raised against recombinant human Troponin I, ensuring precise recognition of its target epitope. Troponin I plays a pivotal role in the troponin complex, which also includes Troponin T (cTnT) and Troponin C (cTnC), by inhibiting actin-myosin interactions in the absence of calcium ions. A key feature of Troponin I is post-translational modifications, particularly phosphorylation, which modulates activity and is essential for the fine-tuning of cardiac muscle contraction and relaxation. Phosphorylation of cTnI at specific serine residues is crucial for the heart′s response to adrenergic stimulation and plays a significant role in cardiac physiology and pathology. Troponin I monoclonal antibody (4) effectively recognizes Troponin I from mouse, rat, and human species, making this product suitable for enzyme-linked immunosorbent assay (ELISA). Understanding the post-translational modifications of Troponin I is vital for investigating cardiac diseases such as myocardial infarction and heart failure, as alterations in phosphorylation patterns can serve as biomarkers for these conditions. Anti-Troponin I antibody (4) provides reliable and specific detection of Troponin I, enabling researchers to study modifications and interactions within the cardiac muscle environment. Troponin I (4) antibody is an indispensable tool for those researching cardiac biomarkers, muscle contraction mechanisms, and related cardiovascular diseases.

The preferred Troponin I antibody is Troponin I Antibody (E-9): sc-365446.