Troponin I Antibody (12): sc-130350

Troponin I Antibody (12) is a mouse monoclonal IgG2b kappa light chain antibody engineered to detect Troponin I, also known as cardiac troponin I (cTnI), a vital regulatory protein within the cardiac muscle contraction machinery. Anti-Troponin I antibody (12) is raised against recombinant human Troponin I, ensuring precise binding to its target epitope and consistent performance across various applications. Troponin I is an essential component of the troponin complex, which also includes Troponin T (cTnT) and Troponin C (cTnC), and is localized within the sarcomere of cardiac muscle cells. The structured domains of Troponin I facilitate its interaction with actin and myosin, effectively regulating muscle contraction in response to calcium ion concentrations. Troponin I monoclonal antibody (12) allows researchers to investigate structural dynamics and interactions with other key proteins, such as actin, myosin, and other troponin subunits, which are crucial for maintaining cardiac function and responding to physiological stimuli. Anti-Troponin I antibody (12) demonstrates robust reactivity with Troponin I from mouse, rat, and human origins, making it versatile for use in western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA) techniques. Understanding the structural role of Troponin I is essential for elucidating the mechanisms underlying cardiac muscle physiology and various pathological conditions, including myocardial infarction and heart failure. Troponin I monoclonal antibody (12) serves as an indispensable tool for researchers focused on cardiac biomarkers, muscle contraction mechanisms, and related disease models.

The preferred Troponin I antibody is Troponin I Antibody (E-9): sc-365446.