TRMT1L Antibody (H-8): sc-515224
- TRMT1L Antibody (H-8) is a mouse monoclonal IgG1 κ TRMT1L antibody provided at 200 µg/ml
- raised against amino acids 231-464 mapping within an internal region of TRMT1L of human origin
- TRMT1L Antibody (H-8) is recommended for detection of TRMT1L of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TRMT1L Antibody (H-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TRMT1L Antibody (H-8) for WB applications. These reagents are now offered in bundles with TRMT1L Antibody (H-8) (see ordering information below).
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TRMT1L Antibody (H-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects TRMT1L protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TRMT1L antibody (H-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRMT1L, or tRNA methyltransferase 1-like, is a member of the methyltransferase family and plays a pivotal role in the post-transcriptional modification of RNA, specifically through the methylation of transfer RNAs (tRNAs). This modification is essential for the stability and functionality of tRNAs, which are critical for the translation of messenger RNA (mRNA) into proteins. TRMT1L catalyzes the addition of methyl groups to specific nucleotide bases within tRNA molecules, thereby influencing their structure, stability, and interactions during protein synthesis. Such modifications are vital for accurate decoding of mRNA codons and efficient protein production, which directly impacts cell growth and differentiation. TRMT1L ensures the fidelity and efficiency of protein translation, serving as a cornerstone of cellular homeostasis and physiological response mechanisms. TRMT1L (H-8) monoclonal antibody enables researchers to gain valuable insights into the intricate processes of RNA modification and its implications in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRMT1L Antibody (H-8) References:
- Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. | Sood, R., et al. 2001. Genomics. 73: 211-22. PMID: 11318611
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. | Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
- The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. | Vauti, F., et al. 2007. Gene. 389: 174-85. PMID: 17198746
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRMT1L Antibody (H-8) | sc-515224 | 200 µg/ml | $316.00 | |||
TRMT1L Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-528006 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRMT1L Antibody (H-8): m-IgG1 BP-HRP Bundle | sc-533379 | 200 µg Ab; 20 µg BP | $354.00 | |||
TRMT1L Antibody (H-8) AC | sc-515224 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TRMT1L Antibody (H-8) HRP | sc-515224 HRP | 200 µg/ml | $316.00 | |||
TRMT1L Antibody (H-8) FITC | sc-515224 FITC | 200 µg/ml | $330.00 | |||
TRMT1L Antibody (H-8) PE | sc-515224 PE | 200 µg/ml | $343.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 488 | sc-515224 AF488 | 200 µg/ml | $357.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 546 | sc-515224 AF546 | 200 µg/ml | $357.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 594 | sc-515224 AF594 | 200 µg/ml | $357.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 647 | sc-515224 AF647 | 200 µg/ml | $357.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 680 | sc-515224 AF680 | 200 µg/ml | $357.00 | |||
TRMT1L Antibody (H-8) Alexa Fluor® 790 | sc-515224 AF790 | 200 µg/ml | $357.00 |