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Trk C Antibody (WW6): sc-80403

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Datasheets
  • Trk C Antibody (WW6) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 100 µg/ml
  • raised against an extracellular domain of Trk C of human origin
  • recommended for detection of Trk C of human origin by WB, IF and IHC(P); non cross-reactive with Trk B
  • See Trk (B-3): sc-7268 for Trk C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Trk C Antibody (WW6). This work is in progress.

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Trk C Antibody (WW6) is a mouse monoclonal IgG2b antibody that detects Trk C in human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Trk C, a member of the tropomyosin receptor kinase family, plays a crucial role in the nervous system by serving as a functional receptor for neurotrophin-3 (NT-3), which is essential for the survival and differentiation of neurons. Anti-Trk C antibody (WW6) helps researchers study neurotrophic signaling, which influences neuronal development and plasticity. Notably, Trk C is primarily expressed in nervous tissue, and various isoforms, produced through alternative splicing, exhibit distinct structural features that may affect their functional roles in neurotrophic signaling pathways. For instance, isoform A is the full-length version, while isoforms B, C, and D have specific deletions that could potentially alter their interaction with NT-3 and other signaling molecules. Trk C monoclonal antibody (WW6) enables researchers to gain insights into the mechanisms of neurotrophic signaling and its implications in neurodevelopmental and neurodegenerative disorders.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trk C Antibody (WW6)

sc-80403
100 µg/ml
$316.00

Can sc-80403: Trk C (WW6) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-80403: Trk C (WW6) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Published data for IHC and WB in human OSCCPublished data for IHC and WB in human OSCC cell lines( KON, HSC-2, HSC-3, HSC-4,Ca9-22 and SAT cells). -SCBT Publication Review
Date published: 2014-10-22
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Trk C Antibody (WW6) is rated 5.0 out of 5 by 1.
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