TRIM9 Antibody (G-4): sc-515007
- TRIM9 Antibody (G-4) is a mouse monoclonal IgG2a κ TRIM9 antibody provided at 200 µg/ml
- raised against amino acids 32-71 mapping near the N-terminus of TRIM9 of human origin
- TRIM9 Antibody (G-4) is recommended for detection of TRIM9 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TRIM9 Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRIM9 Antibody (G-4) for WB applications. These reagents are now offered in bundles with TRIM9 Antibody (G-4) (see ordering information below).
TRIM9 Antibody (G-4) is a mouse monoclonal IgG2a kappa light chain antibody that detects TRIM9 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TRIM9 antibody (G-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRIM9, also known as tripartite motif-containing protein 9 or RING finger protein 91, is a 710 amino acid protein that plays a crucial role in synaptic vesicle exocytosis by regulating SNAP25 availability, a key component of the SNARE complex. This regulation is vital for neurotransmitter release, which is essential for proper neuronal communication and function. TRIM9 contains several characteristic domains, including a RING-type zinc finger, two B box-type zinc fingers, a fibronectin type-III domain, a COS domain, and a B30.2/SPRY domain, which facilitate interactions and functional roles within the cell. TRIM9 exists in three isoforms due to alternative splicing, further diversifying functional capabilities in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRIM9 Antibody (G-4) References:
- The tripartite motif family identifies cell compartments. | Reymond, A., et al. 2001. EMBO J. 20: 2140-51. PMID: 11331580
- TRIM9 is specifically expressed in the embryonic and adult nervous system. | Berti, C., et al. 2002. Mech Dev. 113: 159-62. PMID: 11960705
- HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma. | Lucas, B., et al. 2005. Oncogene. 24: 6418-31. PMID: 16007190
- Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding. | Short, KM. and Cox, TC. 2006. J Biol Chem. 281: 8970-80. PMID: 16434393
- Proteomic profiling reveals that rabies virus infection results in differential expression of host proteins involved in ion homeostasis and synaptic physiology in the central nervous system. | Dhingra, V., et al. 2007. J Neurovirol. 13: 107-17. PMID: 17505979
- Pathogenic rabies virus alters host protein expression in the central nervous system: implications for neuronal dysfunction. | Fu, ZF., et al. 2008. Dev Biol (Basel). 131: 83-91. PMID: 18634469
- Human TRIM gene expression in response to interferons. | Carthagena, L., et al. 2009. PLoS One. 4: e4894. PMID: 19290053
- TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies. | Tanji, K., et al. 2010. Neurobiol Dis. 38: 210-8. PMID: 20085810
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRIM9 Antibody (G-4) | sc-515007 | 200 µg/ml | $322.00 | |||
TRIM9 Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-531261 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM9 Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-524899 | 200 µg Ab, 40 µg BP | $361.00 | |||
TRIM9 Antibody (G-4): m-IgG2a BP-HRP Bundle | sc-547744 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM9 Antibody (G-4) AC | sc-515007 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRIM9 Antibody (G-4) HRP | sc-515007 HRP | 200 µg/ml | $322.00 | |||
TRIM9 Antibody (G-4) FITC | sc-515007 FITC | 200 µg/ml | $336.00 | |||
TRIM9 Antibody (G-4) PE | sc-515007 PE | 200 µg/ml | $349.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 488 | sc-515007 AF488 | 200 µg/ml | $364.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 546 | sc-515007 AF546 | 200 µg/ml | $364.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 594 | sc-515007 AF594 | 200 µg/ml | $364.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 647 | sc-515007 AF647 | 200 µg/ml | $364.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 680 | sc-515007 AF680 | 200 µg/ml | $364.00 | |||
TRIM9 Antibody (G-4) Alexa Fluor® 790 | sc-515007 AF790 | 200 µg/ml | $364.00 |