Date published: 2026-5-20

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Triethyl 2-fluoro-2-phosphonoacetate (CAS 2356-16-3)

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Alternate Names:
2-Fluoro-2-phosphonoacetic acid triethyl ester; Diethyl [(ethoxycarbonyl)fluoromethyl]phosphonate
CAS Number:
2356-16-3
Molecular Weight:
242.18
Molecular Formula:
C8H16FO5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Triethyl 2-fluoro-2-phosphonoacetate is a molecule recognized for its inhibitory effects on the enzyme histone deacetylase. This organic compound contains both fluorine and nitrogen and is classified as one of the geometric isomers of ethyl 2-fluoro-2-phosphonoacetate. Triethyl 2-fluoro-2-phosphonoacetate has demonstrated the ability to inhibit protein synthesis by targeting histone deacetylases. This inhibition causes an increase in the expression of genes associated with cell proliferation and differentiation. Notably, Triethyl 2-fluoro-2-phosphonoacetate exhibits a remarkable selectivity for the retinoic acid receptor beta, potentially due to its strong affinity for this specific subtype of retinoid receptors.


Triethyl 2-fluoro-2-phosphonoacetate (CAS 2356-16-3) References

  1. In Situ Polymerized Flame Retardant Gel Electrolyte for High-Performance and Safety-Enhanced Lithium Metal Batteries.  |  Liu, F., et al. 2023. ACS Appl Mater Interfaces. 15: 23136-23145. PMID: 37141507

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Triethyl 2-fluoro-2-phosphonoacetate, 1 g

sc-253747
1 g
$48.00