TRFP Antibody (G-11): sc-374247
- TRFP Antibody (G-11) is a mouse monoclonal IgG2a κ TRFP antibody provided at 200 µg/ml
- raised against amino acids 32-155 mapping within an internal region of TRFP of human origin
- TRFP Antibody (G-11) is recommended for detection of TRFP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-TRFP Antibody (G-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-374247 X, 200 µg/0.1 ml)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TRFP Antibody (G-11). This work is in progress.
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SEE ALSO...
TRFP Antibody (G-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects TRFP protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TRFP (G-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRFP protein plays a crucial role in the regulation of transcription within mammalian cells, functioning as a coactivator that enhances interaction between transcriptional activators and RNA polymerase II. Proper transcriptional regulation is essential for gene expression, cellular function, and response to environmental signals. TRFP interacts with key components of transcription machinery, including positive coactivator 4 and upstream stimulatory activity of RNA polymerase II and SMCC complex, thereby facilitating both basal and gene-specific transcriptional activation. TRFP (G-11) monoclonal antibody enables researchers to gain valuable insights into mechanisms of transcription regulation and implications in various biological processes and diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRFP Antibody (G-11) References:
- Immunohistochemical telomeric-repeat binding factor-1 expression in gastrointestinal tumors. | Aragona, M., et al. 2000. Oncol Rep. 7: 987-90. PMID: 10948327
- Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas. | Matsutani, N., et al. 2001. Int J Oncol. 19: 507-12. PMID: 11494028
- Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells. | Yajima, T., et al. 2001. Br J Cancer. 85: 752-7. PMID: 11531263
- The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). | Seimiya, H. and Smith, S. 2002. J Biol Chem. 277: 14116-26. PMID: 11854288
- Expression of mRNAs for telomeric repeat binding factor (TRF)-1 and TRF2 in atypical adenomatous hyperplasia and adenocarcinoma of the lung. | Nakanishi, K., et al. 2003. Clin Cancer Res. 9: 1105-11. PMID: 12631614
- Expression of the telomeric repeat binding factor gene NgTRF1 is closely coordinated with the cell division program in tobacco BY-2 suspension culture cells. | Yang, SW., et al. 2003. J Biol Chem. 278: 21395-407. PMID: 12646586
- Nucleolar localization of the human telomeric repeat binding factor 2 (TRF2). | Zhang, S., et al. 2004. J Cell Sci. 117: 3935-45. PMID: 15265990
- Expression of telomeric repeat binding factor-1 in astroglial brain tumors. | La Torre, D., et al. 2005. Neurosurgery. 56: 802-10. PMID: 15792519
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRFP Antibody (G-11) | sc-374247 | 200 µg/ml | $322.00 | |||
TRFP Antibody (G-11) X | sc-374247 X | 200 µg/0.1 ml | $322.00 | |||
TRFP Antibody (G-11) AC | sc-374247 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRFP Antibody (G-11) HRP | sc-374247 HRP | 200 µg/ml | $322.00 | |||
TRFP Antibody (G-11) FITC | sc-374247 FITC | 200 µg/ml | $336.00 | |||
TRFP Antibody (G-11) PE | sc-374247 PE | 200 µg/ml | $349.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 488 | sc-374247 AF488 | 200 µg/ml | $364.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 546 | sc-374247 AF546 | 200 µg/ml | $364.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 594 | sc-374247 AF594 | 200 µg/ml | $364.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 647 | sc-374247 AF647 | 200 µg/ml | $364.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 680 | sc-374247 AF680 | 200 µg/ml | $364.00 | |||
TRFP Antibody (G-11) Alexa Fluor® 790 | sc-374247 AF790 | 200 µg/ml | $364.00 |