TRAPPC2L Antibody (C-5): sc-377322
- TRAPPC2L Antibody (C-5) is a mouse monoclonal IgG1 κ TRAPPC2L antibody provided at 200 µg/ml
- raised against amino acids 21-114 mapping within an internal region of TRAPPC2L of human origin
- TRAPPC2L Antibody (C-5) is recommended for detection of TRAPPC2L of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and bovine
- Anti-TRAPPC2L Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRAPPC2L Antibody (C-5) for WB applications. These reagents are now offered in bundles with TRAPPC2L Antibody (C-5) (see ordering information below).
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TRAPPC2L Antibody (C-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects TRAPPC2L protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TRAPPC2L antibody (C-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRAPPC2L, also known as HSPC126, is a 140 amino acid protein that belongs to the TRAPP small subunits family and the Sedlin subfamily. TRAPPC2L is primarily localized in the cytoplasm, endoplasmic reticulum, and Golgi apparatus, and is expressed in several tissues, including the testis, liver, bladder, lung, spleen, and brain. TRAPPC2L plays a crucial role in vesicular transport from the endoplasmic reticulum to the Golgi apparatus, which is essential for maintaining cellular function and protein trafficking. TRAPPC2L is a member of the multisubunit transport protein particle (TRAPP) complex and interacts with other TRAPP components such as TRAPPC2, TRAPPC3, TRAPPC4, and TRAPPC6A. Notably, TRAPPC2L and TRAPPC2 genes are often found in pairs and exhibit overlapping expression patterns, highlighting their potential cooperative roles in cellular processes. TRAPPC2L exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 16q24.3, a region associated with various genetic disorders, including Rubinstein-Taybi syndrome and Crohn′s disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRAPPC2L Antibody (C-5) References:
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. | Zhang, QH., et al. 2000. Genome Res. 10: 1546-60. PMID: 11042152
- The sequence and analysis of duplication-rich human chromosome 16. | Martin, J., et al. 2004. Nature. 432: 988-94. PMID: 15616553
- Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization. | Turnbull, AP., et al. 2005. EMBO J. 24: 875-84. PMID: 15692564
- High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints. | Gervasini, C., et al. 2007. Genomics. 90: 567-73. PMID: 17855048
- The TRAPP complex: insights into its architecture and function. | Sacher, M., et al. 2008. Traffic. 9: 2032-42. PMID: 18801063
- TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. | Scrivens, PJ., et al. 2009. Traffic. 10: 724-36. PMID: 19416478
- A novel RNA-splicing mutation in TRAPPC2 gene causing x-linked spondyloepiphyseal dysplasia tarda in a large Chinese family. | Guo, H., et al. 2009. J Genet. 88: 87-91. PMID: 19417549
- Transcriptional regulation of bidirectional gene pairs by 17-β-estradiol in MCF-7 breast cancer cells. | Garcia, SA. and Nagai, MA. 2011. Braz J Med Biol Res. 44: 112-22. PMID: 21180879
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRAPPC2L Antibody (C-5) | sc-377322 | 200 µg/ml | $322.00 | |||
TRAPPC2L Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-530008 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRAPPC2L Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-523282 | 200 µg Ab, 40 µg BP | $361.00 | |||
TRAPPC2L Antibody (C-5): m-IgG1 BP-HRP Bundle | sc-543815 | 200 µg Ab; 20 µg BP | $361.00 | |||
TRAPPC2L Antibody (C-5) AC | sc-377322 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRAPPC2L Antibody (C-5) HRP | sc-377322 HRP | 200 µg/ml | $322.00 | |||
TRAPPC2L Antibody (C-5) FITC | sc-377322 FITC | 200 µg/ml | $336.00 | |||
TRAPPC2L Antibody (C-5) PE | sc-377322 PE | 200 µg/ml | $349.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 488 | sc-377322 AF488 | 200 µg/ml | $364.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 546 | sc-377322 AF546 | 200 µg/ml | $364.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 594 | sc-377322 AF594 | 200 µg/ml | $364.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 647 | sc-377322 AF647 | 200 µg/ml | $364.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 680 | sc-377322 AF680 | 200 µg/ml | $364.00 | |||
TRAPPC2L Antibody (C-5) Alexa Fluor® 790 | sc-377322 AF790 | 200 µg/ml | $364.00 |