TRAF4 Antibody (43): sc-136107
- TRAF4 Antibody (43) is a mouse monoclonal IgG1, cited in 2 publications, provided at 50 µg/500 µl
- raised against amino acids 2-160 of TRAF4 of human origin
- recommended for detection of TRAF4 of mouse, rat, human and canine origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TRAF4 Antibody (43). This work is in progress.
TRAF4 Antibody (43) is a mouse monoclonal IgG1 antibody that detects TRAF4 in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). TRAF4, originally known as CART1, plays a crucial role in the signaling pathways of the tumor necrosis factor receptor superfamily, particularly in breast carcinomas where TRAF4 is specifically expressed. TRAF4 is localized to the nucleus, suggesting a role in regulating gene expression and cellular responses to external stimuli. Nuclear localization of TRAF4 is essential for mediating the activation of transcription factors like NFkB, which are pivotal in inflammatory responses and cell survival. TRAF4 interacts with other members of the TRAF family, such as TRAF1, TRAF2, and TRAF3, to form complexes that facilitate signal transduction, thereby influencing various cellular processes including proliferation and apoptosis. The ability of anti-TRAF4 antibody (43) to modulate these pathways highlights TRAF4′s importance in both normal physiology and disease states, making TRAF4 (43) monoclonal antibody a valuable research tool.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRAF4 Antibody (43) | sc-136107 | 50 µg/500 µl | $322.00 |