TPR Antibody (3B9): sc-101294

TPR Antibody (3B9) is a mouse monoclonal IgG1 antibody that detects TPR in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). TPR, or Translocated Promoter Region, plays a crucial role in the nuclear pore complex (NPC), which is essential for the transport of proteins and RNA between the nucleus and cytoplasm. TPR (3B9) antibody recognizes proteins primarily located within the nuclear pore complex, where TPR contributes to the structural integrity and functionality of this vital cellular gateway. The NPC′s ability to regulate the passage of macromolecules is critical for maintaining cellular homeostasis and gene expression, as this regulation ensures that only properly processed molecules enter or exit the nucleus. TPR′s interaction with soluble transport factors through its acidic COOH terminus is particularly important for mediating the export of macromolecules, highlighting TPR′s significance in cellular transport mechanisms. With specific reactivity and versatile applications, anti-TPR antibody (3B9) serves as an invaluable tool for researchers studying nuclear transport processes and the role of the nuclear pore complex in cellular function.

The preferred TPR antibody is TPR Antibody (H-8): sc-271565.