Toxoplasma gondii Antibody (TP3): sc-52255

Toxoplasma gondii Antibody (TP3) is a mouse monoclonal IgG2a antibody that detects Toxoplasma gondii protein by western blotting (WB) and immunofluorescence (IF). Anti-Toxoplasma gondii antibody (TP3) is available as the non-conjugated format. Toxoplasma gondii, a single-celled parasite, maintains a complex life cycle with intestinal and extraintestinal phases. The intestinal phase occurs exclusively in wild and domesticated cats, producing oocysts, while the extraintestinal phase develops in various infected animals, forming tachyzoites and bradyzoites. Tachyzoites play a significant role during acute infection by actively proliferating and invading host tissues, resulting in symptoms like fever and splenomegaly. Understanding Toxoplasma gondii′s life cycle remains crucial, particularly given transmission risks from pregnant women to fetuses, which can cause serious health complications. Toxoplasma gondii (TP3) monoclonal antibody serves as an invaluable research tool for studying pathogenesis and transmission of this significant parasite.

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Toxoplasma gondii Antibody (TP3) References:

1. Toxoplasmosis in pregnancy.  |  Kravetz, JD. and Federman, DG. 2005. Am J Med. 118: 212-6. PMID: 15745715
2. Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis.  |  Lüder, CG. and Gross, U. 2005. Curr Top Microbiol Immunol. 289: 219-37. PMID: 15791958
3. Suspected toxoplasma-associated myocarditis in a cat.  |  Simpson, KE., et al. 2005. J Feline Med Surg. 7: 203-8. PMID: 15922227
4. Toxoplasmosis.  |  Bonfioli, AA. and Orefice, F. 2005. Semin Ophthalmol. 20: 129-41. PMID: 16282146
5. Congenital toxoplasmosis--prenatal aspects of Toxoplasma gondii infection.  |  Rorman, E., et al. 2006. Reprod Toxicol. 21: 458-72. PMID: 16311017
6. Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii.  |  Mazumdar, J., et al. 2006. Proc Natl Acad Sci U S A. 103: 13192-7. PMID: 16920791
7. Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii.  |  Kim, JY., et al. 2006. Korean J Parasitol. 44: 197-207. PMID: 16969057
8. Structures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts.  |  Dubey, JP., et al. 1998. Clin Microbiol Rev. 11: 267-99. PMID: 9564564
9. Advances in the life cycle of Toxoplasma gondii.  |  Dubey, JP. 1998. Int J Parasitol. 28: 1019-24. PMID: 9724872

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Toxoplasma gondii Antibody (TP3) has 10 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Toxoplasma gondii Antibody (TP3) Specifications

Alternate Product Name: Toxoplasma gondii

Product Clone Name: TP3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Toxoplasma gondii

Epitope Species: Toxoplasma gondii

Product Reactivity/Detection: p30 membrane protein of Toxoplasma gondii

Species Reactivity/Detection: Toxoplasma gondii

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for Toxoplasma gondii Antibody (TP3): N/A