Tom20 Antibody (29): sc-136211

Tom20 Antibody (29) is a mouse monoclonal IgG1 kappa light chain antibody that detects Tom20 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Tom20 antibody (29) is available as the non-conjugated form. Tom20 is a crucial component of the mitochondrial preprotein translocases of the outer membrane (Tom) complex, which plays a vital role in importing nucleus-encoded precursor proteins across the mitochondrial outer membrane. Tom20 (29) antibody recognizes a complex essential for mitochondrial function, ensuring proteins necessary for energy production and metabolic processes are properly imported into mitochondria. The Tom machinery consists of various import receptors, including Tom20 and Tom22, which form a heteromeric receptor complex that initiates the insertion of newly synthesized proteins into the outer membrane and directs them into the general import pore (GIP). Tom20 interacts with Tom22, which is essential for the docking and translocation of preproteins, thereby facilitating efficient incorporation of Tom40 precursors into preexisting Tom complexes. Proper functioning of this import system is critical, as disruptions can lead to mitochondrial dysfunction and are implicated in various diseases, including neurodegenerative disorders.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Tom20 Antibody (29) has 30 citations in a variety of scientific publications.

Primary antibodies like Anti-Tom20 Antibody (29) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Tom20 Antibody (29) Specifications

Alternate Product Name: Tom20

Product Clone Name: 29

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 47-145

Epitope Target: Tom20

Epitope Species: human

Product Reactivity/Detection: Tom20

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 30 citations in various scientific publications

Available Conjugates/Forms for Tom20 Antibody (29): N/A

The preferred Tom20 antibody is Tom20 Antibody (F-10): sc-17764.