TNF-R2 Antibody (TR75-32): sc-12751
- TNF-R2 Antibody (TR75-32) is a Armenian hamster monoclonal IgG, cited in 2 publications, provided at 200 µg/ml
- raised against recombinant mouse TNF RII extracellular domain
- recommended for detection of TNF-R2 of mouse origin by IP, IF and IHC(P)
- also available conjugated to biotin for WB, IHC(P) and ELISA
- also provided azide-free for neutralization, sc-12751 L, 200 µg/0.1 ml
- See TNF-R2 (TR75-89): sc-12750 for TNF-R2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TNF-R2 Antibody (TR75-32). This work is in progress.
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TNF-R2 Antibody (TR75-32) is a hamster monoclonal IgG antibody that detects TNF-R2 in mouse samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. TNF-R2, also known as tumor necrosis factor receptor 2, plays a crucial role in mediating the effects of tumor necrosis factor (TNF), a key cytokine involved in inflammation and immune responses. This receptor is primarily expressed on immune cells and is essential for regulating cell survival, proliferation, and differentiation. TNF-R2 signaling is associated with anti-apoptotic pathways, which can influence the outcome of various immune responses and contribute to the pathogenesis of autoimmune diseases and cancer. The interaction of TNF-R2 with TNF can lead to the recruitment of various signaling molecules, including TRAF2 and TRAF1, which are pivotal for downstream signaling cascades that promote cell survival and inflammatory responses. Understanding the dynamics of TNF-R2 and its interactions is vital for developing therapeutic strategies targeting inflammatory diseases and malignancies, making TNF-R2 monoclonal antibody (TR75-32) an invaluable tool for researchers studying these complex biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF-R2 Antibody (TR75-32) | sc-12751 | 200 µg/ml | $322.00 | |||
TNF-R2 Antibody (TR75-32) B | sc-12751 B | 200 µg/ml | $326.00 | |||
TNF-R2 Antibody (TR75-32) L | sc-12751 L | 200 µg/0.1 ml | $322.00 |