TNF-R2 Antibody (F-3): sc-393614

TNF-R2 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects TNF-R2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TNF-R2, also known as tumor necrosis factor receptor 2, plays a crucial role in mediating the effects of tumor necrosis factor (TNF), a key cytokine involved in inflammation and immune responses. TNF-R2 is primarily expressed on immune cells and is essential for regulating cell survival, proliferation, and differentiation. TNF-R2 signaling is associated with anti-apoptotic effects, which can influence the progression of various diseases, including cancer and autoimmune disorders. TNF-R2 interaction with TNF activates downstream signaling pathways that can lead to the activation of transcription factors such as NF-kB, promoting cell survival and inflammatory responses. Understanding TNF-R2 function and signaling mechanisms is vital for developing therapeutic strategies targeting inflammatory diseases and cancer, making anti-TNF-R2 antibody (F-3) an invaluable tool for researchers studying these critical biological processes.

The preferred TNF-R2 antibody is TNF-R2 Antibody (D-2): sc-8041.