TNF-R1 Antibody (G-2): sc-374185
- TNF-R1 Antibody (G-2) is a mouse monoclonal IgG2a κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 427-454 at the C-terminus of TNF-R1 of mouse origin
- recommended for detection of TNF-R1 of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- See TNF-R1 (H-5): sc-8436 for TNF-R1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TNF-R1 Antibody (G-2). This work is in progress.
TNF-R1 Antibody (G-2) is a mouse monoclonal IgG1 antibody that detects tumor necrosis factor receptor 1 (TNF-R1) in mouse and rat samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TNF-R1 plays a crucial role in mediating the effects of tumor necrosis factor, a key cytokine involved in systemic inflammation and immune responses. TNF-R1 is predominantly located on the surface of most cell types, allowing TNF-R1 to initiate a wide range of cellular responses, including apoptosis, cell survival, and inflammation. TNF-R1′s ability to transduce signals that lead to apoptosis is particularly important in regulating immune responses and maintaining tissue homeostasis. Dysregulation of TNF-R1 signaling has been implicated in various pathological conditions, including autoimmune diseases and cancer, making TNF-R1 a significant target for therapeutic intervention. Anti-TNF-R1 antibody (G-2) is essential for researchers studying these pathways, providing a reliable tool for the detection and analysis of TNF-R1 in diverse biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF-R1 Antibody (G-2) | sc-374185 | 200 µg/ml | $316.00 | |||
TNF-R1 (G-2) Neutralizing Peptide | sc-374185 P | 100 µg/0.5 ml | $68.00 |