Date published: 2026-1-10

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TNF alpha Antibody (AS1): sc-52791

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Datasheets
  • TNF alpha Antibody (AS1) is a mouse monoclonal IgG1, cited in 3 publications, provided at 100 µg/ml
  • recommended for detection of TNFα of human origin by WB, IP and ELISA; non cross-reactive with human TNF β or a panel of other human cytokines
  • available conjugated to FITC for IF, IHC(P) and FCM
  • See TNF alpha (C-4): sc-133192 for TNF alpha antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TNF alpha Antibody (AS1). This work is in progress.

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TNFα Antibody (AS1) is a mouse monoclonal IgG1 antibody that detects tumor necrosis factor α (TNFα) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TNFα is a critical cytokine involved in systemic inflammation and is produced by various immune cells, including lymphocytes, neutrophils, and macrophages. TNFα plays a vital role in the immune response by regulating the activity of other immune cells and promoting the inflammatory process, which is essential for fighting infections and healing injuries. TNFα can also induce apoptosis in certain tumor cells, making TNFα a key player in cancer biology. The interaction of TNFα with its receptors, particularly TNF receptor 1 and TNF receptor 2, is crucial for mediating diverse biological effects, including cell survival, proliferation, and differentiation. TNFα′s ability to modulate immune responses and involvement in various diseases, such as rheumatoid arthritis and inflammatory bowel disease, underscores the importance of studying this cytokine. Anti-TNFα antibody (AS1) is an invaluable tool for researchers investigating the complex roles of TNFα in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TNF alpha Antibody (AS1)

sc-52791
100 µg/ml
$322.00

TNF alpha Antibody (AS1) FITC

sc-52791 FITC
200 µg/ml

For Western Blot, is it recommended to use denatured or non-denatured conditions with TNFα (AS1): sc-52791 antibody?

Asked by: jenniferc
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2020-11-06
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Rated 4 out of 5 by from Works well for WB with good signalWorks well for WB with good signal. -SCBT QC
Date published: 2013-05-21
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TNF alpha Antibody (AS1) is rated 4.0 out of 5 by 1.
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