TNF alpha Antibody (4E1): sc-130349
- TNF alpha Antibody (4E1) is a mouse monoclonal IgG1, cited in 33 publications, provided at 200 µg/ml
- raised against recombinant TNFα of human origin
- TNF alpha Antibody (4E1) is recommended for detection of TNFα of human origin by WB, IP, IF and IHC(P)
- Anti-TNF alpha Antibody (4E1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TNF alpha Antibody (4E1) for WB and IHC(P) applications. These reagents are now offered in bundles with TNF alpha Antibody (4E1) (see ordering information below).
QUICK LINKS
TNFα Antibody (4E1) is a mouse monoclonal IgG1 antibody that detects TNFα of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-TNFα antibody (4E1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Tumor necrosis factor alpha (TNFα), also known as cachectin, is a critical cytokine involved in systemic inflammation and is produced by lymphocytes, neutrophils, and macrophages. TNFα (4E1) monoclonal antibody plays a crucial role in studying immune responses and inflammation, which is vital for the body′s defense against infections and tumors. TNFα interacts with two primary receptors, TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2), which are essential for biological activity. Binding of TNFα to these receptors triggers signaling pathways leading to cell survival, apoptosis, or activation of inflammatory responses. This multifaceted role underscores TNFα′s importance in both normal immune function and pathological conditions, such as autoimmune diseases and cancer, making TNFα (4E1) antibody a valuable research tool.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF alpha Antibody (4E1) | sc-130349 | 200 µg/ml | $316.00 | |||
TNF alpha Antibody (4E1): m-IgG Fc BP-HRP Bundle | sc-527082 | 200 µg Ab; 10 µg BP | $354.00 | |||
TNF alpha Antibody (4E1): m-IgG1 BP-HRP Bundle | sc-532455 | 200 µg Ab; 20 µg BP | $354.00 | |||
TNF alpha Antibody (4E1) AC | sc-130349 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TNF alpha Antibody (4E1) HRP | sc-130349 HRP | 200 µg/ml | $316.00 | |||
TNF alpha Antibody (4E1) FITC | sc-130349 FITC | 200 µg/ml | $330.00 | |||
TNF alpha Antibody (4E1) PE | sc-130349 PE | 200 µg/ml | $343.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 488 | sc-130349 AF488 | 200 µg/ml | $357.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 546 | sc-130349 AF546 | 200 µg/ml | $357.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 594 | sc-130349 AF594 | 200 µg/ml | $357.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 647 | sc-130349 AF647 | 200 µg/ml | $357.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 680 | sc-130349 AF680 | 200 µg/ml | $357.00 | |||
TNF alpha Antibody (4E1) Alexa Fluor® 790 | sc-130349 AF790 | 200 µg/ml | $357.00 |