TMIGD2 Antibody (H-5): sc-515546

TMIGD2 Antibody (H-5) is a mouse monoclonal IgM antibody that detects TMIGD2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-TMIGD2 antibody (H-5) is available as a non-conjugated antibody. TMIGD2, also known as transmembrane and immunoglobulin domain-containing protein 2, is a 282 amino acid single-pass type I membrane protein characterized by one immunoglobulin-like domain and exists in two alternatively spliced isoforms. TMIGD2 plays a crucial role in cell signaling and immune response regulation, particularly in T cell activation and differentiation. The gene encoding TMIGD2 is located on human chromosome 19p13.3, a region known for high gene density and significant involvement in immune system functions, housing various immunoglobulin superfamily members. Understanding TMIGD2 function is vital, as TMIGD2 may contribute to the development of therapeutic strategies targeting immune-related diseases and conditions.

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TMIGD2 Antibody (H-5) References:

1. C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers.  |  Wang, L., et al. 2000. Clin Cancer Res. 6: 2988-93. PMID: 10955775
2. The genomic context of natural killer receptor extended gene families.  |  Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
3. Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome.  |  Le Meur, N., et al. 2004. Eur J Hum Genet. 12: 415-8. PMID: 14970844
4. Comparative human-mouse-rat sequence analysis of the ICAM gene cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q.  |  Leeb, T. and Müller, M. 2004. Gene. 343: 239-44. PMID: 15588578
5. The extended human leukocyte receptor complex: diverse ways of modulating immune responses.  |  Barrow, AD. and Trowsdale, J. 2008. Immunol Rev. 224: 98-123. PMID: 18759923
6. Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region.  |  Olsen, A., et al. 1994. Genomics. 23: 659-68. PMID: 7851895
7. The pregnancy-specific glycoprotein (PSG) gene cluster on human chromosome 19: fine structure of the 11 PSG genes and identification of 6 new genes forming a third subgroup within the carcinoembryonic antigen (CEA) family.  |  Teglund, S., et al. 1994. Genomics. 23: 669-84. PMID: 7851896

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TMIGD2 Antibody (H-5) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-TMIGD2 Antibody (H-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TMIGD2 Antibody (H-5) Specifications

Alternate Product Name: TMIGD2

Product Clone Name: H-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 247-269

Epitope Target: TMIGD2

Epitope Species: human

Product Reactivity/Detection: TMIGD2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for TMIGD2 Antibody (H-5): P: Blocking Peptide