TMEM40 Antibody (A-9): sc-393601
- TMEM40 Antibody (A-9) is a mouse monoclonal IgG1 κ TMEM40 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-51 mapping at the N-terminus of TMEM40 of human origin
- TMEM40 Antibody (A-9) is recommended for detection of TMEM40 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-TMEM40 Antibody (A-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for TMEM40 Antibody (A-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with TMEM40 Antibody (A-9) (see ordering information below).
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SEE ALSO...
TMEM40 Antibody (A-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects TMEM40 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TMEM40 (A-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Transmembrane protein 40 (TMEM40) is a 233 amino acid multi-pass membrane protein that exists in two isoforms and is localized to chromosome 3p25.1, a region known for involvement in various genetic disorders and cancers. TMEM40 plays a significant role in collagen-induced arthritis, highlighting TMEM40′s importance in inflammatory processes. Additionally, TMEM40′s location within the cell membrane suggests involvement in cellular signaling pathways and interactions with extracellular matrix components, which are crucial for maintaining tissue integrity and mediating cellular responses to environmental cues. Chromosome 3, where TMEM40 is located, is notable for harboring a chemokine receptor gene cluster and several loci associated with human cancers, including key tumor suppressor genes that regulate apoptosis and cell migration. Understanding TMEM40′s function and interactions can provide insights into potential roles in disease mechanisms and therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMEM40 Antibody (A-9) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. | Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193
- High resolution mapping of Cia3: a common arthritis quantitative trait loci in different species. | Yu, X., et al. 2009. J Immunol. 182: 3016-23. PMID: 19234197
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM40 Antibody (A-9) | sc-393601 | 200 µg/ml | $316.00 | |||
TMEM40 Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-526258 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM40 Antibody (A-9) AC | sc-393601 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TMEM40 Antibody (A-9) HRP | sc-393601 HRP | 200 µg/ml | $316.00 | |||
TMEM40 Antibody (A-9) FITC | sc-393601 FITC | 200 µg/ml | $330.00 | |||
TMEM40 Antibody (A-9) PE | sc-393601 PE | 200 µg/ml | $343.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 488 | sc-393601 AF488 | 200 µg/ml | $357.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 546 | sc-393601 AF546 | 200 µg/ml | $357.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 594 | sc-393601 AF594 | 200 µg/ml | $357.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 647 | sc-393601 AF647 | 200 µg/ml | $357.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 680 | sc-393601 AF680 | 200 µg/ml | $357.00 | |||
TMEM40 Antibody (A-9) Alexa Fluor® 790 | sc-393601 AF790 | 200 µg/ml | $357.00 |