TMEM230 Antibody (G-2): sc-398561

TMEM230 Antibody (G-2) is a mouse monoclonal IgG3 kappa light chain antibody that detects TMEM230 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMEM230 (G-2) antibody is available as the non-conjugated form, providing researchers with a reliable tool for studying this important protein. TMEM230 protein is primarily located in the endoplasmic reticulum and is involved in the regulation of synaptic vesicle trafficking, which is crucial for neurotransmitter release and neuronal communication. Understanding the localization and function of TMEM230 is vital, as disruptions in synaptic vesicle dynamics can lead to various neurological disorders, including neurodegenerative diseases. Additionally, chromosome 20, where TMEM230 gene is located, harbors several other genes implicated in male reproductive health and neurological conditions, highlighting the significance of this region in both reproductive biology and neurobiology. With robust performance in multiple applications, anti-TMEM230 antibody (G-2) is an essential reagent for advancing research in these critical areas.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

TMEM230 Antibody (G-2) References:

1. Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?  |  Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
2. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.  |  Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
3. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
4. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
5. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
6. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
7. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
8. Cellular pathways leading to neuronal dysfunction and degeneration.  |  Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
9. The prion diseases.  |  Prusiner, SB. 1998. Brain Pathol. 8: 499-513. PMID: 9669700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TMEM230 Antibody (G-2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-TMEM230 Antibody (G-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TMEM230 Antibody (G-2) Specifications

Alternate Product Name: TMEM230

Product Clone Name: G-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 16-41

Epitope Target: TMEM230

Epitope Species: human

Product Reactivity/Detection: TMEM230

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for TMEM230 Antibody (G-2): P: Blocking Peptide