TMEM111 Antibody (A-12): sc-365903
- TMEM111 Antibody (A-12) is a mouse monoclonal IgG2a κ TMEM111 antibody, cited in 7 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 51-83 within an internal region of TMEM111 of human origin
- TMEM111 Antibody (A-12) is recommended for detection of TMEM111 of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- Anti-TMEM111 Antibody (A-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMEM111 Antibody (A-12) for WB and IHC(P) applications. These reagents are now offered in bundles with TMEM111 Antibody (A-12) (see ordering information below).
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TMEM111 Antibody (A-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects TMEM111 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-TMEM111 antibody (A-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TMEM111, also known as POB, is a 261 amino acid multi-pass membrane protein that plays a crucial role in cellular processes, including regulation of apoptosis and cell signaling pathways. TMEM111′s presence in the membrane is vital for maintaining cellular homeostasis and facilitating communication between cells, which is essential for normal physiological functions. TMEM111 exists as multiple alternatively spliced isoforms, which adds complexity to functional roles and may influence interactions with other proteins. TMEM111′s gene is located on human chromosome 3, a region associated with various genetic diseases and key tumor suppressor genes, highlighting TMEM111′s importance in both health and disease contexts. Understanding TMEM111′s function and interactions can provide insights into potential roles in cancer biology and other pathologies, making TMEM111 (A-12) monoclonal antibody a valuable tool for researchers studying these critical processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMEM111 Antibody (A-12) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM111 Antibody (A-12) | sc-365903 | 200 µg/ml | $316.00 | |||
TMEM111 Antibody (A-12): m-IgG Fc BP-HRP Bundle | sc-529504 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM111 Antibody (A-12): m-IgGκ BP-HRP Bundle | sc-522414 | 200 µg Ab, 40 µg BP | $354.00 | |||
TMEM111 Antibody (A-12) AC | sc-365903 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TMEM111 Antibody (A-12) HRP | sc-365903 HRP | 200 µg/ml | $316.00 | |||
TMEM111 Antibody (A-12) FITC | sc-365903 FITC | 200 µg/ml | $330.00 | |||
TMEM111 Antibody (A-12) PE | sc-365903 PE | 200 µg/ml | $343.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 488 | sc-365903 AF488 | 200 µg/ml | $357.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 546 | sc-365903 AF546 | 200 µg/ml | $357.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 594 | sc-365903 AF594 | 200 µg/ml | $357.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 647 | sc-365903 AF647 | 200 µg/ml | $357.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 680 | sc-365903 AF680 | 200 µg/ml | $357.00 | |||
TMEM111 Antibody (A-12) Alexa Fluor® 790 | sc-365903 AF790 | 200 µg/ml | $357.00 | |||
TMEM111 (A-12) Neutralizing Peptide | sc-365903 P | 100 µg/0.5 ml | $68.00 |