TLR4 Antibody (76B357.1): sc-52962

TLR4 Antibody (76B357.1) is a mouse monoclonal IgG2b kappa light chain antibody that detects TLR4 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Anti-TLR4 antibody (76B357.1) is available in a non-conjugated form, allowing for versatile applications in research. TLR4, a member of the Toll-like receptor family, plays a crucial role in the innate immune response by recognizing pathogen-associated molecular patterns, particularly lipopolysaccharides from Gram-negative bacteria. This recognition triggers a cascade of signaling events that lead to the activation of nuclear factor kappa B (NFkB) and the subsequent production of pro-inflammatory cytokines, which are essential for mounting an effective immune response. TLR4 is predominantly located on the surface of immune cells such as macrophages and dendritic cells, where expression is vital for the detection of infections and the initiation of inflammatory responses. Understanding the function and signaling pathways of TLR4 is important for developing therapeutic strategies against various infectious diseases and inflammatory conditions. Anti-TLR4 antibody (76B357.1) serves as an invaluable tool for researchers studying immune responses and the mechanisms of inflammation.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TLR4 Antibody (76B357.1) has 23 citations in a variety of scientific publications.

Primary antibodies like Anti-TLR4 Antibody (76B357.1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TLR4 Antibody (76B357.1) Specifications

Alternate Product Name: TLR4

Product Clone Name: 76B357.1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: TLR4

Epitope Species: human

Product Reactivity/Detection: TLR4

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, FCM

Vialing Information: Each vial contains 100 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 23 citations in various scientific publications

Available Conjugates/Forms for TLR4 Antibody (76B357.1): N/A

The preferred TLR4 antibody is TLR4 Antibody (25): sc-293072.