TIMP-2 Antibody (B-12): sc-365671
- TIMP-2 Antibody (B-12) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 190-220 near the C-terminus of TIMP-2 of human origin
- recommended for detection of TIMP-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- See TIMP-2 (3A4): sc-21735 for TIMP-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TIMP-2 Antibody (B-12) for WB applications. These reagents are now offered in bundles with TIMP-2 Antibody (B-12) (see ordering information below).
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TIMP-2 Antibody (B-12) is a mouse monoclonal IgG1 antibody that detects TIMP-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TIMP-2, or tissue inhibitor of metalloproteinase 2, plays a crucial role in regulating extracellular matrix remodeling by inhibiting metalloproteinases, which are enzymes responsible for the degradation of various components of the extracellular matrix. This regulation is vital for maintaining tissue homeostasis and facilitating processes such as wound healing and embryonic development. Notably, TIMP-2 interacts with matrix metalloproteinases (MMPs) like MMP-2 and MMP-9, effectively preventing excessive tissue breakdown and promoting cellular stability. TIMP-2 expression is particularly important in various physiological and pathological contexts, including cancer progression, where TIMP-2 levels can influence tumor growth and metastasis. With an ability to modulate MMP activity, TIMP-2 serves as a key player in both normal physiological processes and disease states, making anti-TIMP-2 antibody (B-12) an essential tool for researchers studying these critical biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIMP-2 Antibody (B-12) | sc-365671 | 200 µg/ml | $322.00 | |||
TIMP-2 Antibody (B-12): m-IgG Fc BP-HRP Bundle | sc-540358 | 200 µg Ab; 10 µg BP | $361.00 | |||
TIMP-2 Antibody (B-12): m-IgG1 BP-HRP Bundle | sc-542065 | 200 µg Ab; 20 µg BP | $361.00 | |||
TIMP-2 (B-12) Neutralizing Peptide | sc-365671 P | 100 µg/0.5 ml | $69.00 |