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TIM Antibody (BB-7) is a mouse monoclonal IgG1 antibody that detects Triosephosphate Isomerase (TIM) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TIM is a crucial enzyme in the glycolytic pathway, facilitating the reversible conversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate, which are essential intermediates in glucose metabolism. This enzymatic activity is vital for energy production, as TIM plays a key role in the generation of pyruvate and ATP from glucose, thereby supporting cellular respiration and energy homeostasis. TIM is predominantly located in the cytosol, where TIM participates in the glycolytic process, and proper functioning is critical for maintaining metabolic balance. Mutations or deficiencies in TIM can lead to significant metabolic disorders, including non-spherocytic hemolytic anemia and other serious health issues, underscoring TIM′s importance in both normal physiology and disease states. Anti-TIM antibody (BB-7) is an invaluable tool for researchers studying glycolysis and its implications in metabolic diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIM Antibody (BB-7) | sc-100541 | 100 µg/ml | $339.00 |