TID-1_L/S Antibody (RS-11): sc-18820

TID-1L/S Antibody (RS-11) is a mouse monoclonal IgG1 antibody that detects TID-1L/S in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). TID-1L/S plays a crucial role in the regulation of apoptosis, a vital process for maintaining cellular homeostasis and preventing tumorigenesis. TID-1L/S is localized in the mitochondrial matrix, where TID-1L/S influences apoptotic signal transduction by modulating the release of cytochrome c and the activation of caspase-3, both of which are key events in the apoptotic pathway. TID-1L and TID-1S in mitochondria underscore their importance in cellular responses to stress and damage, as these proteins help determine cell fate by either promoting or inhibiting apoptosis depending on expression levels and J domain integrity. Notably, TID-1L and TID-1S are generated from the same gene through alternative splicing, and differential expression can significantly impact the apoptotic response, making TID-1L and TID-1S critical targets for research in cancer biology and therapeutic interventions. TID-1L/S (RS-11) antibody is an essential tool for studying these processes and understanding the complex mechanisms of apoptosis in various biological contexts.

The preferred TID-1_L/S antibody is TID-1_L/S Antibody (RS-13): sc-18819.